(10α,24R)-9β-Methyl-19-norlanosta-5-ene-3β,11α,24,25-tetrol
- CAS No.
- 88930-15-8
- Chemical Name:
- (10α,24R)-9β-Methyl-19-norlanosta-5-ene-3β,11α,24,25-tetrol
- Synonyms
- Mogrol;Mogrol, >98%;Monascus alcohol;(24R)-Cucurbit-5-ene-3β,11α,24,25-tetrol;(10α,24R)-9β-Methyl-19-norlanosta-5-ene-3β,11α,24,25-tetrol;(10α,24R)-9β-Methyl-19-norlanosta-5-ene-3β,11α,24,25-tetrol;(10α,24R)-3β,11α,24,25-Tetrahydroxy-9β-methyl-19-norlanosta-5-ene;ERK,inhibit,Extracellular signal regulated kinases,STAT,Mogrol,Inhibitor
- CBNumber:
- CB12165711
- Molecular Formula:
- C30H52O4
- Molecular Weight:
- 476.73
- MDL Number:
- MFCD29904541
- MOL File:
- 88930-15-8.mol
| Boiling point | 595.6±50.0 °C(Predicted) |
|---|---|
| Density | 1.10±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | 14.67±0.29(Predicted) |
| CAS DataBase Reference | 88930-15-8 |
(10α,24R)-9β-Methyl-19-norlanosta-5-ene-3β,11α,24,25-tetrol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL84241 | Mogrol phyproof? Reference Substance | 88930-15-8 | 10MG | $629 | 2024-03-01 | Buy |
| ChemScene | CS-6010 | Mogrol 98.06% | 88930-15-8 | 25mg | $640 | 2021-12-16 | Buy |
| ChemScene | CS-6010 | Mogrol 98.06% | 88930-15-8 | 5mg | $190 | 2021-12-16 | Buy |
| ChemScene | CS-6010 | Mogrol 98.06% | 88930-15-8 | 1mg | $65 | 2021-12-16 | Buy |
| ChemScene | CS-6010 | Mogrol 98.06% | 88930-15-8 | 10mg | $320 | 2021-12-16 | Buy |
(10α,24R)-9β-Methyl-19-norlanosta-5-ene-3β,11α,24,25-tetrol Chemical Properties,Uses,Production
Appearance
Constit. of Cucurbita foeridissimia (buffalo gourd).Amorph. powder.
Definition
ChEBI: Mogrol is a tetracyclic triterpenoid that is cucurbitadienol in which the side-chain double bond (position 24-25) has undergone formal oxidation to introduce hydroxy groups at positions 24 and 25 (the 24R stereoisomer). It is a biometabolite of mogrosides found in Siraitia grosvenorii. It has a role as an antineoplastic agent. It is a tetracyclic triterpenoid and a hydroxy seco-steroid. It is functionally related to a cucurbitadienol.
Biochem/physiol Actions
Mogrol is an aglycone of mogrosides from Siraitia grosvenorii that exhibits neuroprotective and anticancer activities. It induces apoptosis in K562 leukemia cells through suppression of ERK1/2 and STAT3 pathways. Mogrol appears to ameliorate the memory impairment caused by Aβ1-42 in mice. Mogrol increases AMPK activity in hepatocytes and suppresses adipocyte differentiation in 3T3-L1 cells.
(10α,24R)-9β-Methyl-19-norlanosta-5-ene-3β,11α,24,25-tetrol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | marketing1@neostarunited.com | China | 8348 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9634 | 58 |
