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ChemicalBook >> CAS DataBase List >>1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea

1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea

1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Structure
1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea structure
CAS No.
839713-36-9
Chemical Name:
1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
Synonyms
APD125;APD 125;APD-125;Nelotanserin;APD125(Nelotanserin);APD125;APD-125;APD 125;APD125; APD-125; APD 125; NELOTANSERIN;1-[3-(4-bromo-2-methylpyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea;1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea;1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
CBNumber:
CB12484964
Molecular Formula:
C18H15BrF2N4O2
Molecular Weight:
437.24
MDL Number:
MFCD16619341
MOL File:
839713-36-9.mol
Last updated:2023-05-21 10:59:17
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1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Properties

Boiling point 425.9±45.0 °C(Predicted)
Density 1.55±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:32.0(Max Conc. mg/mL);73.2(Max Conc. mM)
pka 12.29±0.70(Predicted)
FDA UNII 4ZA73QEW2P

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC N389655 Nelotanserin 839713-36-9 5mg $165 2021-12-16 Buy
TRC N389655 Nelotanserin 839713-36-9 25mg $670 2021-12-16 Buy
ChemScene CS-5984 Nelotanserin 99.79% 839713-36-9 100mg $750 2021-12-16 Buy
Biosynth Carbosynth FB101032 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea 839713-36-9 100mg $370 2021-12-16 Buy
ChemScene CS-5984 Nelotanserin 99.79% 839713-36-9 50mg $450 2021-12-16 Buy
Product number Packaging Price Buy
N389655 5mg $165 Buy
N389655 25mg $670 Buy
CS-5984 100mg $750 Buy
FB101032 100mg $370 Buy
CS-5984 50mg $450 Buy

1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Chemical Properties,Uses,Production

Uses

Nelotanserin is a potent selective 5-HT2A inverse agonist, nelotanserin has low nanomolar potency on the 5-HT2A receptor with at least 30- and 5000-fold selectivity compared with 5-HT2C and 5-HT2B receptors.

Definition

ChEBI: Nelotanserin is a member of pyrazoles and a ring assembly.

1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Preparation Products And Raw materials

Raw materials

Preparation Products

1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Suppliers

Global( 55)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49391 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 11013 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501 product@acmec-e.com China 33350 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 4604 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 17702719238 sales@sun-shinechem.com China 918 64
Supplier Advantage
CONIER CHEM AND PHARMA LIMITED 		58
Career Henan Chemica Co 		58
TargetMol Chemicals Inc. 		58
Zibo Hangyu Biotechnology Development Co., Ltd 		58
LEAPCHEM CO., LTD. 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58
Aladdin Scientific 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
Amadis Chemical Company Limited 		58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 64
1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Urea, N-[3-(4-broMo-1-Methyl-1H-pyrazol-5-yl)-4-Methoxyphenyl]-N'-(2,4-difluorophenyl)- Nelotanserin 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea APD125(Nelotanserin) APD 125 APD125 APD-125 APD125;APD-125;APD 125 APD125; APD-125; APD 125; NELOTANSERIN 1-[3-(4-bromo-2-methylpyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea 5-HT Receptor,Inhibitor,APD 125,inhibit,APD-125,Nelotanserin,Serotonin Receptor,5-hydroxytryptamine Receptor 839713-36-9