ChemicalBook >> CAS DataBase List >>4-[5-(4-Butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridinehydrochloride
4-[5-(4-Butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridinehydrochloride
![4-[5-(4-Butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridinehydrochloride Structure](CAS/GIF/388575-52-8.gif)
- CAS No.
- 388575-52-8
- Chemical Name:
- 4-[5-(4-Butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridinehydrochloride
- Synonyms
- PSN375963;PSN 375963 hydrochloride;5-(4-butylcyclohexyl)-3-pyridin-4-yl-1,2,4-oxadiazole;4-[5-(4-butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridine;Pyridine, 4-[5-(4-butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-;4-[5-(4-Butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridinehydrochloride;Inhibitor,inhibit,PSN375963,receptor,PSN 375963,PSN-375963,G Protein-Coupled Receptor 119,endogenous,GPR119,ligand,orphan,cAMP
- CBNumber:
- CB12518900
- Molecular Formula:
- C17H23N3O
- Molecular Weight:
- 285.38
- MDL Number:
- MFCD01829706
- MOL File:
- 388575-52-8.mol
- MSDS File:
- SDS
Last updated:2023-09-04 15:51:00
| Boiling point | 440.1±47.0 °C(Predicted) |
|---|---|
| Density | 1.060±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: >10mg/mL |
| pka | 0.82±0.10(Predicted) |
| form | powder |
| color | white to off-white |
| FDA UNII | C9M28M425E |
4-[5-(4-Butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridinehydrochloride price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P0028 | PSN-375963 ≥98% (HPLC) | 388575-52-8 | 25mg | $358 | 2022-05-15 | Buy |
| Cayman Chemical | 10008593 | PSN375963 ≥98% | 388575-52-8 | 1mg | $18 | 2024-03-01 | Buy |
| Cayman Chemical | 10008593 | PSN375963 ≥98% | 388575-52-8 | 5mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 10008593 | PSN375963 ≥98% | 388575-52-8 | 10mg | $129 | 2024-03-01 | Buy |
| Cayman Chemical | 10008593 | PSN375963 ≥98% | 388575-52-8 | 25mg | $278 | 2024-03-01 | Buy |
4-[5-(4-Butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridinehydrochloride Chemical Properties,Uses,Production
Biochem/physiol Actions
PSN-375963 is a GPR119 partial agonist. GPR119 is an orphan GPCR, expressed predominantly in pancreas and GI tract, that has been characterized. Its endogenous ligands are oleoylethanolamide (OEA) and oleoyl-lysophosphatidylcholine, lipid signaling molecules that regulate food intake and body weight. OEA decreases food intake, so GPR119 agonists are potential therapies for obesity. Initial studies showed that PSN-375963 has similar potency and partial efficacy compared to OEA. Further studies revealed that although OEA and PSN-375963 are GPR119 agonists, they have divergent effects on insulin secretion, calcium signaling, and cAMP production.
4-[5-(4-Butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridinehydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 42)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4663 | 58 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3244 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| Supplier | Advantage |
|---|---|
| ATK CHEMICAL COMPANY LIMITED | 60 |
| TargetMol Chemicals Inc. | 58 |
| Aladdin Scientific | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 69 |
| Dalian Meilun Biotech Co., Ltd. | 58 |
| LETOPHARM LIMITED | 58 |
| Sigma-Aldrich | 80 |
| EMMX Biotechnology LLC | 60 |
| Angel Pharmatech, Ltd. | 58 |
| BOC Sciences | 65 |
4-[5-(4-Butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridinehydrochloride
PSN 375963 hydrochloride
PSN375963
4-[5-(4-butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridine
5-(4-butylcyclohexyl)-3-pyridin-4-yl-1,2,4-oxadiazole
Inhibitor,inhibit,PSN375963,receptor,PSN 375963,PSN-375963,G Protein-Coupled Receptor 119,endogenous,GPR119,ligand,orphan,cAMP
Pyridine, 4-[5-(4-butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-
388575-52-8
C17H23N3OHCl