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N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine

N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine structure

CAS No.: 232271-19-1

Chemical Name:: N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine

Synonyms: MDK1191;MDK-1191;TR 14035;TR-14035;TR 14035;TR14035;TR 14035;TR14035;MDK-1191;MDK1191;N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine;(S)-2-(2,6-DichlorobenzaMido)-3-(2',6'-diMethoxy-[1,1'-biphenyl]-4-yl)propanoic acid;(S)-2-(2,6-Dichlorobenzamido)-3-(2',6'-dimethoxy-[1,1'-biphenyl]-4-yl)propanoic acid;[1,1'-Biphenyl]-4-propanoic acid, α-[(2,6-dichlorobenzoyl)amino]-2',6'-dimethoxy-, (αS)-;(alphaS)-alpha-[(2,6-Dichlorobenzoyl)amino]-2',6'-dimethoxy-[1,1'-biphenyl]-4-propanoic acid

CBNumber:: CB12565722

Molecular Formula:: C24H21Cl2NO5

Molecular Weight:: 474.33

MDL Number:: MFCD09970400

MOL File:: 232271-19-1.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

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N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine Properties

Boiling point	604.0±55.0 °C(Predicted)
Density	1.333
storage temp.	2-8°C
solubility	DMSO: ≥ 41 mg/mL (86.44 mM)
form	Powder
pka	3.53±0.10(Predicted)
FDA UNII	UW585PBD7S

N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	6908	TR14035 ≥98%(HPLC)	232271-19-1	50	$905	2021-12-16	Buy
Biorbyt Ltd	orb573451	TR-14035 >98%	232271-19-1	100mg	$1060.8	2021-12-16	Buy
ChemScene	CS-1812	TR-14035 95.14%	232271-19-1	50mg	$1080	2021-12-16	Buy
Activate Scientific	AS43383	TR 14035 98% ee	232271-19-1	5mg	$145	2021-12-16	Buy
Activate Scientific	AS43383	TR 14035 98% ee	232271-19-1	25mg	$286	2021-12-16	Buy

Product number	Packaging	Price	Buy
6908	50	$905	Buy
orb573451	100mg	$1060.8	Buy
CS-1812	50mg	$1080	Buy
AS43383	5mg	$145	Buy
AS43383	25mg	$286	Buy

N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine Chemical Properties,Uses,Production

Biological Activity

TR-14035 (SB 683698, MDK-1191) is a dual alpha4beta (α4β) integrin antagonist with IC50 values of 7 nM and 87 nM for alpha4beta7 (α4β7) and alpha4beta1 (α4β1), respectively.

in vitro

TR-14035 blocks adhesion of RPMI-8866 cells to MAdCAM-Ig by 100% at 1 μM, with an approximate IC ₅₀ of 0.01 μM.

target

Target	Value
α4β7 (Cell-free assay)	7 nM
α4β1 (Cell-free assay)	87 nM

storage

Store at -20°C

N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine Preparation Products And Raw materials

Raw materials

Preparation Products

N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine Suppliers

Global( 57)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chengdu Feibo Pharm Technology Co., Ltd	15982321820	abby@arkpharm.com	CHINA	3279	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2923	55

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
Chengdu Feibo Pharm Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
InvivoChem	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Shanghai Boyle Chemical Co., Ltd.	55

232271-19-1(N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine)Related Search:

Carbon tetrachloride 3,5-Dichlorobenzoic acid 4,4'-Dichlorodiphenyl sulfone Xylene Dichloroethane

TR 14035 (S)-2-(2,6-DichlorobenzaMido)-3-(2',6'-diMethoxy-[1,1'-biphenyl]-4-yl)propanoic acid N-(2,6-Dichlorobenzoyl)-4-(2,6-diMethoxyphenyl)-L-phenylalanine (alphaS)-alpha-[(2,6-Dichlorobenzoyl)amino]-2',6'-dimethoxy-[1,1'-biphenyl]-4-propanoic acid MDK1191 MDK-1191 TR 14035;TR14035;MDK-1191;MDK1191 TR-14035;TR 14035;TR14035 [1,1'-Biphenyl]-4-propanoic acid, α-[(2,6-dichlorobenzoyl)amino]-2',6'-dimethoxy-, (αS)- (S)-2-(2,6-Dichlorobenzamido)-3-(2',6'-dimethoxy-[1,1'-biphenyl]-4-yl)propanoic acid[TR14035 TR-14035,autoimmune,disease,asthma,TR14035,Integrin,inhibit,TR 14035,allergic,inflammation,Inhibitor,alpha(4) (S)-2-(2,6-Dichlorobenzamido)-3-(2',6'-dimethoxy-[1,1'-biphenyl]-4-yl)propanoic acid 232271-19-1