9-Nitrooleate
- CAS No.
- 875685-44-2
- Chemical Name:
- 9-Nitrooleate
- Synonyms
- 9-Nitrooleate;9-Nitro Oleic Acid;(9E)-9-Nitro-9-octadecenoic Acid;9-Octadecenoic acid, 9-nitro-, (9E)-
- CBNumber:
- CB12590135
- Molecular Formula:
- C18H33NO4
- Molecular Weight:
- 327.45892
- MDL Number:
- MFCD12912273
- MOL File:
- 875685-44-2.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
|
9-Nitrooleate price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10008042 | 9-Nitrooleate ≥98% | 875685-44-2 | 50μg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 10008042 | 9-Nitrooleate ≥98% | 875685-44-2 | 100μg | $50 | 2024-03-01 | Buy |
| Cayman Chemical | 10008042 | 9-Nitrooleate ≥98% | 875685-44-2 | 500μg | $207 | 2024-03-01 | Buy |
| Cayman Chemical | 10008042 | 9-Nitrooleate ≥98% | 875685-44-2 | 1mg | $359 | 2024-03-01 | Buy |
| Usbiological | 018252 | 9-Nitrooleic Acid | 875685-44-2 | 100ug | $233 | 2021-12-16 | Buy |
9-Nitrooleate Chemical Properties,Uses,Production
Description
Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate (LNO2; ), cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules. LNO2 isomers serve as potent endogenous ligands for PPARγ and can also decompose or be metabolized to release nitric oxide. 9-Nitrooleate is one of two regioisomers of nitrooleate, the other being 10-nitrooleate (OA-NO2; used for the mixture of isomers), which are formed by nitration of oleic acid in approximately equal proportions in vivo. Peroxynitrite, acidified nitrite, and myeloperoxidase in the presence of H2O2 and nitrite, all mediate the nitration of oleic acid. OA-NO2 is found in human plasma as the free acid and esterified in phospholipids at concentrations of 619 ± 52 nM and 302 ± 369 nM, respectively. OA-NO2 activates PPARγ approximately 7-fold at a concentration of 1 μM and effectively promotes the differentiation of 3T3-L1 preadiopcytes to adipocytes at 3 μM.
Uses
9-Nitrooleic Acid is a bioactive, nitric-oxide derived fatty acid. 9-Nitrooleic Acid thats acts as an irreversible inhibitor of xanthine oxidoreductase. 9-Nitrooleic Acid is a novel antagonist of Ang II-induced hypertension. 9-Nitrooleic Acid is an endogenous PPAR agonist which may offer an effective and safe therapeutic intervention for obesity and obesity-related conditions.
Uses
9-Nitrooleic Acid is a bioactive, nitric-oxide derived fatty acid. 9-Nitrooleic Acid II-induced hypertension. 9-Nitrooleic Acid is an endogenous PPAR agonist which may offer an effective and safe therapeutic intervention for obesity and obesity-related conditions.
Definition
ChEBI: (9E)-9-nitrooctadecenoic acid is a nitro fatty acid that is (9E)-octadec-9-enoic (elaidic) acid substituted by a nitro group at position 9. It has a role as a human metabolite. It is a long-chain fatty acid, a monounsaturated fatty acid and a nitro fatty acid. It is functionally related to an elaidic acid.
9-Nitrooleate Preparation Products And Raw materials
Raw materials
Preparation Products
9-Nitrooleate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 19949 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55954 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| amyjetsci | 027-59626688 18771149750 | sales@amyjet.com | China | 3004 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.com | China | 24246 | 58 |