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Polygalacin D

CAS No.
66663-91-0
Chemical Name:
Polygalacin D
Synonyms
Onjisaponin D;Polygalacin D;Polygalacin D2;Olean-12-en-28-oic acid, 3-(β-D-glucopyranosyloxy)-2,16,23-trihydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,4β,16α)-
CBNumber:
CB12614224
Molecular Formula:
C57H92O27
Molecular Weight:
1209.34
MDL Number:
MFCD28009141
MOL File:
66663-91-0.mol
Last updated:2023-08-28 18:13:45

Polygalacin D Properties

Density 1.54±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 4°C, protect from light
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka 12.76±0.70(Predicted)

Polygalacin D price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 300806 Polygalacin D 66663-91-0 10mg $632 2021-12-16 Buy
Biorbyt Ltd orb259443 Polygalacin D 98% 66663-91-0 5mg $433.5 2021-12-16 Buy
ChemScene CS-0032282 PolygalacinD 99.30% 66663-91-0 5mg $457 2021-12-16 Buy
ChemScene CS-0032282 PolygalacinD 99.30% 66663-91-0 1mg $152 2021-12-16 Buy
Biorbyt Ltd orb259443 Polygalacin D 98% 66663-91-0 10mg $591.6 2021-12-16 Buy
Product number Packaging Price Buy
300806 10mg $632 Buy
orb259443 5mg $433.5 Buy
CS-0032282 5mg $457 Buy
CS-0032282 1mg $152 Buy
orb259443 10mg $591.6 Buy

Polygalacin D Chemical Properties,Uses,Production

Chemical Properties

White needle crystal. Soluble in water, ethanol, methanol and other solvents, insoluble in petroleum ether, chloroform, ethyl acetate.

Definition

ChEBI: Polygalacin D is a triterpenoid saponin. It has a role as a metabolite.

Biological Activity

Polygalacin D (PGD) is a bioactive compound with anticancer and antiproliferative properties isolated from Platycodon grandiflorum. It inhibits the expression of the IAP protein family, including survivin, cIAP-1 and cIAP-2 proteins, and blocks the PI3K/Akt pathway by inhibiting GSK3β, Akt phosphorylation and PI3K expression. It induces apoptosis through the PI3K/Akt pathway.

target

NOS | COX | PGE | NO | NF-kB

Polygalacin D Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 81)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907 qinhe02@xaltbio.com China 1000 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
Chengdu Greenpure Biopharma CO.,Ltd
18283602253 jancyzheng@gcgreenpure.com China 952 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Aktin Chemicals, Inc.
028-85159085 info@aktinchem.com CHINA 1025 58
Apeloa Pharmaceutical Co., Ltd.
+86-0571-87635730 +8615858229168 chem1022@hengdian-group.com China 1469 58

View Lastest Price from Polygalacin D manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Polygalacin D pictures 2024-04-12 Polygalacin D
66663-91-0
US $0.00 / kg 1kg 99% 2000ton Shaanxi Haibo Biotechnology Co., Ltd
Polygalacin D pictures 2023-02-24 Polygalacin D
66663-91-0
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
Polygalacin D pictures 2020-03-10 Polygalacin D
66663-91-0
US $16.00 / KG 1KG 98% 1kg, 10kg, 50kg Career Henan Chemical Co
  • Polygalacin D pictures
  • Polygalacin D
    66663-91-0
  • US $0.00 / kg
  • 99%
  • Shaanxi Haibo Biotechnology Co., Ltd
  • Polygalacin D pictures
  • Polygalacin D
    66663-91-0
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
  • Polygalacin D pictures
  • Polygalacin D
    66663-91-0
  • US $16.00 / KG
  • 98%
  • Career Henan Chemical Co
Polygalacin D Onjisaponin D Olean-12-en-28-oic acid, 3-(β-D-glucopyranosyloxy)-2,16,23-trihydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,4β,16α)- Polygalacin D2 66663-91-0 C57H92O27