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ChemicalBook >> CAS DataBase List >>3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)-

3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)-

3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- Structure
3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- structure
CAS No.
120964-45-6
Chemical Name:
3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)-
Synonyms
DZNepHCl;NSC 617989 HCl;DZNEP; NSC 617989;DZNep hydrochloride;3-deazaneplanocin A HCl;NSC 617989 hydrochloride;3-deazaneplanocin A (DZNeP) HCl;3-Deazaneplanocin hydrochloride;DZNeP (3-deazaneplanocin A) HCl;3-Deazaneplanocin A (hydrochloride)
CBNumber:
CB12623932
Molecular Formula:
C12H15ClN4O3
Molecular Weight:
298.7255
MDL Number:
MFCD18782644
MOL File:
120964-45-6.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59
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3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- Properties

Melting point 168-169℃
storage temp. -20°C
solubility H2O: ≥5mg/mL
form Tan solid
color white to beige
Water Solubility Soluble in water (10mM)
InChIKey UNSKMHKAFPRFTI-FDKLLANESA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3

3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0305 3-Deazaneplanocin A hydrochloride ≥97% (HPLC) 120964-45-6 1mg $473 2024-03-01 Buy
Sigma-Aldrich 252790 Histone Methyltransferase EZH2 Inhibitor, DZNep 120964-45-6 2mg $303 2024-03-01 Buy
Cayman Chemical 11102 3-Deazaneplanocin A (hydrochloride) ≥98% 120964-45-6 500μg $92 2024-03-01 Buy
Cayman Chemical 11102 3-Deazaneplanocin A (hydrochloride) ≥98% 120964-45-6 1mg $174 2024-03-01 Buy
Sigma-Aldrich SML0305 3-Deazaneplanocin A hydrochloride ≥97% (HPLC) 120964-45-6 5mg $1590 2024-03-01 Buy
Product number Packaging Price Buy
SML0305 1mg $473 Buy
252790 2mg $303 Buy
11102 500μg $92 Buy
11102 1mg $174 Buy
SML0305 5mg $1590 Buy

3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- Chemical Properties,Uses,Production

Uses

3-Deazaneplanocin A is a a powerful inhibitor of S-adenosylhomocysteine hydrolase that has shown potent and selective in vitro and in vivo antiviral activities.

Uses

3-Deazaneplanocin A hydrochloride has been used to test its effect on ovarian tumor progression. It has also been used as a S-adenosyl homocysteine hydrolase (SAH) inhibitor in c33A2 cells.

General Description

3-Deazaneplanocin A hydrochloride is a carbocyclic analog of adenosine. It has antimetastatic?property. It is used to treat Ebola virus disease, gastric cancer, myeloma and lymphoma.

Biochem/physiol Actions

3-Deazaneplanocin A (DZNep) is an S-Adenosylhomocysteine Hydrolase inhibitor and histone methyltransferase EZH2 inhibitor. It switches on repressed tumor suppressor genes and induces apoptosis by inhibiting the expression of EZH2.

target

histone methyltransferase

storage

-20°C

3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- Preparation Products And Raw materials

Raw materials

Preparation Products

3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- Suppliers

Global( 94)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9341 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 28455 58
Baoji Guokang Bio-Technology Co., Ltd. 		0917-3909592 13892490616 gksales1@gk-bio.com China 9335 58
NewCan Biotech Limited 		+86-0571-86912261 +8613735419629 sales@newcanbio.com China 9975 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Supplier Advantage
Hangzhou FandaChem Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
Hubei Jusheng Technology Co.,Ltd. 		58
career henan chemical co 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Dideu Industries Group Limited 		58
Baoji Guokang Bio-Technology Co., Ltd. 		58
NewCan Biotech Limited 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58

View Lastest Price from 3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Deazaneplanocin A hydrochloride pictures 2021-07-13 3-Deazaneplanocin A hydrochloride
120964-45-6
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
3-Deazaneplanocin A hydrochloride pictures 2021-07-09 3-Deazaneplanocin A hydrochloride
120964-45-6
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- pictures 2019-12-24 3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)-
120964-45-6
 US $1.00 / g 1g 99.99% 200kg Career Henan Chemical Co

3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- Spectrum

3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)-(120964-45-6)1HNMR

120964-45-6(3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)-)Related Search:

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3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- 3-Deazaneplanocin A (hydrochloride) 3-Deazaneplanocin hydrochloride DZNep hydrochloride NSC 617989 hydrochloride (-)-1-[(1R,4R,5S)-3-(HydroxyMethyl)-4,5-dihydroxy-2-cyclopenten-1-yl]4-aMinoiMidazo[4,5-c]pyridine hydrochloride DZNep hydrochloride (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride (1:1) 1H-Imidazo[4,5-c]pyridine, 3-cyclopentene-1,2-diol deriv. 3-deazaneplanocin A HCl 3-deazaneplanocin A (DZNeP) HCl NSC 617989 HCl (-)-1-[(1R,4R,5S)-3-(Hydroxymethyl)-4,5-dihydroxy-2-cyclopenten-1-yl]4-aminoimidazo[4,5-c]pyridine hydrochloride Histone Methyltransferase EZH2 Inhibitor, DZNep Histone Methyltransferase EZH2 Inhibitor, DZNep - CAS 120964-45-6 - Calbiochem DZNEP; NSC 617989 (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride 3-Deazaneplanocin A (DZNep) hydrochloride DZNEP HYDROCHLORIDE;NSC 617989 HYDROCHLORIDE;3-DEAZANEPLANOCIN HYDROCHLORIDE 3-deazaneplanocin A HCl (DZNep HCl) DZNepHCl 3-Deazaneplanocin A hydrochloride (DZNep hydrochloride 3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- USP/EP/BP (1S,2R,5R)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol DZNeP (3-deazaneplanocin A) HCl 120964-45-6 C12H14N4O3HCl C12H14N4O3ClH Inhibitors 1