ChemicalBook >> CAS DataBase List >>N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide

N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide

N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide structure

CAS No.: 1314891-22-9

Chemical Name:: N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide

Synonyms: TFMO 2;TMP 195;CS-2651;TMP195; TMP-195;TMP 195 - TFMO 2;TMP-195;TMP195;TMP 195;Inhibitor,TMP195,TMP-195,HDAC,Histone deacetylases,inhibit;N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide;Benzamide, N-[2-methyl-2-(2-phenyl-4-oxazolyl)propyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-

CBNumber:: CB12667558

Molecular Formula:: C23H19F3N4O3

Molecular Weight:: 456.42

MDL Number:: MFCD26522024

MOL File:: 1314891-22-9.mol

Last updated:2023-09-04 15:50:00

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N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide Properties

Density	1.303±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 0.2 mg/ml
form	A crystalline solid
pka	13.05±0.46(Predicted)

N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide price More Price(13)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	23242	TMP-195 ≥98%	1314891-22-9	1mg	$32	2024-03-01	Buy
Cayman Chemical	23242	TMP-195 ≥98%	1314891-22-9	5mg	$139	2024-03-01	Buy
Cayman Chemical	23242	TMP-195 ≥98%	1314891-22-9	10mg	$243	2024-03-01	Buy
Cayman Chemical	23242	TMP-195 ≥98%	1314891-22-9	25mg	$571	2024-03-01	Buy
ChemScene	CS-7000	TMP195 99.68%	1314891-22-9	50mg	$792	2021-12-16	Buy

Product number	Packaging	Price	Buy
23242	1mg	$32	Buy
23242	5mg	$139	Buy
23242	10mg	$243	Buy
23242	25mg	$571	Buy
CS-7000	50mg	$792	Buy

N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide Chemical Properties,Uses,Production

Biological Activity

TMP195 (TFMO 2) is a selective class IIa HDAC inhibitor with IC50 of 300 nM in cell-based assays.

in vitro

TMP195 has low potency in recombinant class I and class IIb HDAC assays, and is able to completely inhibit class IIa HDAC activity without inhibiting other HDACs. In the supernatant of monocyte-derived macrophage differentiation medium, it prevented the accumulation of CCL2 protein; compared with the control group, it could significantly increase the level of CCL1 protein secreted by monocytes.

target

Target	Value
HDAC9 (Cell-free assay)	15 nM(Ki)
HDAC7 (Cell-free assay)	26 nM(Ki)
HDAC4 (Cell-free assay)	59 nM(Ki)
HDAC5 (Cell-free assay)	60 nM(Ki)

N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide Preparation Products And Raw materials

Raw materials

Preparation Products

N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide Suppliers

Global( 59)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
ShangHai YuanYe Biotechnology Co., Ltd.	021-61312847 13636370518	shyysw007@163.com	China	4941	60

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
Career Henan Chemica Co	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
InvivoChem	58
TargetMol Chemicals Inc.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
ShangHai YuanYe Biotechnology Co., Ltd.	60

N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide Spectrum

N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide(1314891-22-9)¹HNMR

1314891-22-9(N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide)Related Search:

TMP269 TMP778

TFMO 2 N-[2-Methyl-2-(2-phenyloxazol-4-yl)propyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]benzaMide TMP 195 TMP-195;TMP195;TMP 195 CS-2651 TMP 195 - TFMO 2 TMP195; TMP-195 Inhibitor,TMP195,TMP-195,HDAC,Histone deacetylases,inhibit Benzamide, N-[2-methyl-2-(2-phenyl-4-oxazolyl)propyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]- 1314891-22-9 API