ChemicalBook >> CAS DataBase List >>Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite
Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite
- CAS No.
- 1391728-01-0
- Chemical Name:
- Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite
- Synonyms
- Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite;O-2-cyanoethyl-O'-(3,6-dioxanon-8-ynyl)-N,N-diisopropylphosphoramidite;Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 2-[2-(2-propyn-1-yloxy)ethoxy]ethyl ester
- CBNumber:
- CB13062620
- Molecular Formula:
- C16H29N2O4P
- Molecular Weight:
- 344.39
- MDL Number:
- MFCD28142480
- MOL File:
- 1391728-01-0.mol
Last updated:2023-07-14 17:32:04
Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | BP-22317 | Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite Tech | 1391728-01-0 | 100mg | $430 | 2021-12-16 | Buy |
| BroadPharm | BP-22317 | Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite Tech | 1391728-01-0 | 250mg | $750 | 2021-12-16 | Buy |
| Apolloscientific | BIPG1737 | Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite | 1391728-01-0 | 100mg | $837 | 2021-12-16 | Buy |
| BroadPharm | BP-22317 | Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite Tech | 1391728-01-0 | 500mg | $1125 | 2021-12-16 | Buy |
Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite Chemical Properties,Uses,Production
Biological Activity
Propargyl-PEG3-1-o-b-cyanoethyl-NN-diisopropylphosphoramidite is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite Suppliers
Global( 13)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1246 | 55 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6357 | 58 | |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 029-86217788 13892832556 | 2440688701@qq.com | China | 1992 | 58 |
| Shanghai Jiange Chemical Co., Ltd. | 15921040873 | 1434142450@qq.com | CHINA | 7651 | 58 |
| Shaanxi borno biotechnology co., LTD | +86-13759708231 | asherw9@hotmail.com | China | 2351 | 58 |
| Zhengzhou anmousse chemical products co. LTD | 0371-55289822 18737195735 | 483339295@qq.com | China | 7092 | 58 |
| Shanghai Sunway Pharmaceutical Technology Co.,Ltd. | 021-51816796-820 13611835272 | sales2@sunwaypharm.com | China | 44486 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 29778 | 58 |
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Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite
O-2-cyanoethyl-O'-(3,6-dioxanon-8-ynyl)-N,N-diisopropylphosphoramidite
Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 2-[2-(2-propyn-1-yloxy)ethoxy]ethyl ester
1391728-01-0
C16H29N2O4P