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ChemicalBook >> CAS DataBase List >>(4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4a,5a,6,9,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one2-oxide

(4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4a,5a,6,9,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one2-oxide

(4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4a,5a,6,9,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one2-oxide Structure
(4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4a,5a,6,9,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one2-oxide structure
CAS No.
150829-29-1
Chemical Name:
(4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4a,5a,6,9,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one2-oxide
Synonyms
EOS-60323;Fosdenopterin;Lenacapavir Impurity 14;(4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4a,5a,6,9,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one2-oxide;1,3,2-Dioxaphosphorino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one, 8-amino-4a,5a,6,9,11,11a,12,12a-octahydro-2,12,12-trihydroxy-, 2-oxide, (4aR,5aR,11aR,12aS)-
CBNumber:
CB13142269
Molecular Formula:
C10H14N5O8P
Molecular Weight:
363.22
MDL Number:
MFCD34567165
MOL File:
150829-29-1.mol
MSDS File:
SDS
Last updated:2024-01-16 14:13:58
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(4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4a,5a,6,9,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one2-oxide Properties

Boiling point 736.8±70.0 °C(Predicted)
Density 2.86±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka 1.07±0.40(Predicted)
FDA UNII 4X7K2681Y7

(4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4a,5a,6,9,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one2-oxide Chemical Properties,Uses,Production

Uses

Nulibry is a cyclic pyranopterin monophosphate (cPMP) used for treatment of molybdenum cofactor deficiency type A.

Definition

ChEBI: Precursor Z hydrate is a linear-fused organic heterotetracyclic compound consisting of a [1,3,2]dioxaphosphinane fused to a pyran ring which is in turn fused to a pteridine ring system. Molybdenum cofactor biosynthesis intermediate. Dehydrated derivative known as precursor Z. It has a role as an Escherichia coli metabolite. It is an organic heterotetracyclic compound, an oxacycle, an organonitrogen heterocyclic compound and a ketone hydrate.

(4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4a,5a,6,9,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one2-oxide synthesis

1394061-94-9
150829-29-1
Synthesis of (4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4a,5a,6,9,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one2-oxide from 4H-Pyrano[3,2-g]pteridin-4-one, 2-amino-3,5,5a,6,7,8,9a,10-octahydro-6,7-dihydroxy-8-(hydroxymethyl)-, (5aS,6R,7R,8R,9aR)-

(4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4a,5a,6,9,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one2-oxide Preparation Products And Raw materials

Raw materials

4H-Pyrano[3,2-g]pteridin-4-one, 2-amino-3,5,5a,6,7,8,9a,10-octahydro-6,7-dihydroxy-8-(hydroxymethyl)-, (5aS,6R,7R,8R,9aR)- 1,3,2-Dioxaphosphorino[4',5':5,6]pyrano[3,2-g]pteridine-6(5aH)-carboxylic acid, 8-[bis[(1,1-dimethylethoxy)carbonyl]amino]-4,4a,9,10,11,11a,12,12a-octahydro-12,12-dihydroxy-2-methoxy-10-oxo-, 1,1-dimethylethyl ester, 2-oxide, (4aR,5aR,11aR,12aS)-

Preparation Products

(4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4a,5a,6,9,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one2-oxide Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangsu shring Biopharma Co., Ltd. 		+8613372282299 sales@shringchem.com China 3545 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Wuhan Demeikai Biotechnology Co., Ltd +8618942921723 info@dmksw.xin China 723 58
Jinan elephant international trading co., LTD 13006575422@163.com China 6357 58
Shanghai zhigan biotechnology co., LTD zhiqianbio@126.com China 19785 58
BEIJING INNO-TECH PHARMIC TECHNOLOGY CO.,LTD 15011485209 China 145 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24018 58
guoyungurui 18162595016 3287908757@qq.com China 10012 58
Supplier Advantage
Jiangsu shring Biopharma Co., Ltd. 		58
TargetMol Chemicals Inc. 		58
Wuhan Demeikai Biotechnology Co., Ltd 58
Jinan elephant international trading co., LTD 58
Shanghai zhigan biotechnology co., LTD 58
BEIJING INNO-TECH PHARMIC TECHNOLOGY CO.,LTD 58
TargetMol Chemicals Inc. 58
guoyungurui 58

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(4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4a,5a,6,9,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one2-oxide EOS-60323 Fosdenopterin 1,3,2-Dioxaphosphorino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one, 8-amino-4a,5a,6,9,11,11a,12,12a-octahydro-2,12,12-trihydroxy-, 2-oxide, (4aR,5aR,11aR,12aS)- Lenacapavir Impurity 14 150829-29-1