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CC-885

CAS No.
1010100-07-8
Chemical Name:
CC-885
Synonyms
CC-885;Ligands for E3 Ligase,CC-885,CC 885,E3 ligase-recruiting Moiety,CC885,Inhibitor,inhibit;1-(3-Chloro-4-methylphenyl)-3-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)urea;Urea, N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-
CBNumber:
CB13159377
Molecular Formula:
C22H21ClN4O4
Molecular Weight:
440.88
MDL Number:
MFCD31657329
MOL File:
1010100-07-8.mol
Last updated:2023-04-23 13:52:06

CC-885 Properties

solubility DMSO:40.0(Max Conc. mg/mL);90.72(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.45(Max Conc. mM)
DMF:12.5(Max Conc. mg/mL);28.35(Max Conc. mM)
form A crystalline solid

CC-885 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19966 CC-885 ≥98% 1010100-07-8 500μg $90 2024-03-01 Buy
Cayman Chemical 19966 CC-885 ≥98% 1010100-07-8 1mg $171 2024-03-01 Buy
Cayman Chemical 19966 CC-885 ≥98% 1010100-07-8 5mg $578 2024-03-01 Buy
Cayman Chemical 19966 CC-885 ≥98% 1010100-07-8 10mg $886 2024-03-01 Buy
AK Scientific 1485DC 1-(3-Chloro-4-methylphenyl)-3-[[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]methyl]urea 1010100-07-8 1mg $293 2021-12-16 Buy
Product number Packaging Price Buy
19966 500μg $90 Buy
19966 1mg $171 Buy
19966 5mg $578 Buy
19966 10mg $886 Buy
1485DC 1mg $293 Buy

CC-885 Chemical Properties,Uses,Production

Description

CC-885 is a potent Cereblon Modulator with potent antitumor activity mediated through the degradation of GSPT1. was demonstrated to mediate antitumor effects through the recruitment and degradation of G1 to S phase transition 1 protein (GSPT1). GSPT1 (also named eRF3a) is a translation termination factor that binds eukaryotic translation termination factor 1 (eFR1) to mediate stop codon recognition and nascent protein release from the ribosome.

target

CC-885 is a cereblon (CRBN) modulator.

CC-885 Preparation Products And Raw materials

Raw materials

Preparation Products

CC-885 Suppliers

Global( 57)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd
+8618235132063 sales@tihondan.com China 3725 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Wuhan Jingkang en Biomedical Technology Co., Ltd
+8613720134139 orders@jknbiochem.com China 4664 58
CC-885 Urea, N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]- 1-(3-Chloro-4-methylphenyl)-3-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)urea Ligands for E3 Ligase,CC-885,CC 885,E3 ligase-recruiting Moiety,CC885,Inhibitor,inhibit 1010100-07-8