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PD-1/PD-L1 Inhibitor 3

PD-1/PD-L1 Inhibitor 3 Structure
PD-1/PD-L1 Inhibitor 3 structure
CAS No.
1629654-95-0
Chemical Name:
PD-1/PD-L1 Inhibitor 3
Synonyms
PD-1/PD-L1-IN 3;PD-1/PD-L1 Inhibitor 3;PD-1/PD-L1 Inhibitor 3 TFA;PD-1/PD-L1 Inhibitor 3 USP/EP/BP;Glycinamide, N-(2-mercaptoacetyl)-L-phenylalanyl-N-methyl-L-alanyl-L-asparaginyl-L-prolyl-L-histidyl-L-leucyl-N-methylglycyl-L-tryptophyl-L-seryl-L-tryptophyl-N-methyl-L-norleucyl-N-methyl-L-norleucyl-L-arginyl-L-cysteinyl-, cyclic (1→14)-thioether
CBNumber:
CB13362748
Molecular Formula:
C89H126N24O18S
Molecular Weight:
1852.17
MDL Number:
MFCD32645111
MOL File:
1629654-95-0.mol
Last updated:2023-05-21 10:59:17
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PD-1/PD-L1 Inhibitor 3 Properties

Density 1.42±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 13.14±0.70(Predicted)

PD-1/PD-L1 Inhibitor 3 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ApexBio Technology B6191 PD-1/PD-L1Inhibitor3 1629654-95-0 5mg $1047 2021-12-16 Buy
DC Chemicals DC44154 PD-1/PD-L1-IN3 >98% 1629654-95-0 25mg $750 2021-12-16 Buy
Product number Packaging Price Buy
B6191 5mg $1047 Buy
DC44154 25mg $750 Buy

PD-1/PD-L1 Inhibitor 3 Chemical Properties,Uses,Production

Biological Activity

pd-1/pd-l1 inhibitor 3 is a pd-1/pd-l1 interaction inhibitor.the anti-pd-1 and anti-pd-l1 compounds have been found to show impressive antitumor effects in various malignancies, such as melanoma. the greatest clinical outcome in unselected patients has been observed in melanoma. the tumor expression of pd-l1 is suggested to be a suggestive, inadequate, and predictive of response to immune-checkpoint blockade.

in vitro

pd-1/pd-l1 inhibitor 3 has been identified to be a potent and selective small molecule inhibitor blocking the interaction of programmed cell death protein 1 (pd-1) with its ligand protein (pd-l1) and with cd80. pd-1/pd-l1 inhibitor 3 was also found to act as an immunomodulator. in addition, pd-1/pd-l1 inhibitor 3 was found to have highly efficacious binding to pd-l1 and promote the increased functional activities of t cells. therefore, pd-1/pd-l1 inhibitor 3 could be regarded as a promising therapeutic treatment of cancer and infectious diseases, such as hepatitis c [1].

target

TargetValue
PD-1/PD-L1 interaction
(Cell-free assay )		 5.6 nM

References

[1] miller michael matthew, et al. patent, pub. no.:wo/2014/151634

PD-1/PD-L1 Inhibitor 3 Preparation Products And Raw materials

Raw materials

Preparation Products

PD-1/PD-L1 Inhibitor 3 Suppliers

Global( 44)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10247 58
Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10297 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 6011 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 27690 58
BOC Sciences 		16314854226; +16314854226 inquiry@bocsci.com United States 19743 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
LEAP CHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 24738 58
Hebei Miaoyin Technology Co.,Ltd 		+86-17367732028 +86-17367732028 kathy@hbyinsheng.com China 3582 58
Supplier Advantage
Shenzhen Nexconn Pharmatechs Ltd 		58
Fuxin Pharmaceutical 		58
Hebei Yanxi Chemical Co., Ltd. 		58
Career Henan Chemica Co 		58
Dideu Industries Group Limited 		58
BOC Sciences 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
InvivoChem 		58
LEAP CHEM CO., LTD. 		58
Hebei Miaoyin Technology Co.,Ltd 		58

View Lastest Price from PD-1/PD-L1 Inhibitor 3 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PD-1/PD-L1 Inhibitor 3 pictures 2023-05-27 PD-1/PD-L1 Inhibitor 3
1629654-95-0
 US $45.00 / kg 1kg 99% 20tons Henan Bao Enluo International TradeCo.，LTD
PD-1/PD-L1 Inhibitor 3 USP/EP/BP pictures 2021-08-18 PD-1/PD-L1 Inhibitor 3 USP/EP/BP
1629654-95-0
 US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited

1629654-95-0(PD-1/PD-L1 Inhibitor 3)Related Search:

PD-1/PD-L1 Inhibitor 4 PALLADIUM ON STRONTIUM CARBONATE, REDUCED
PD-1/PD-L1 Inhibitor 3 Glycinamide, N-(2-mercaptoacetyl)-L-phenylalanyl-N-methyl-L-alanyl-L-asparaginyl-L-prolyl-L-histidyl-L-leucyl-N-methylglycyl-L-tryptophyl-L-seryl-L-tryptophyl-N-methyl-L-norleucyl-N-methyl-L-norleucyl-L-arginyl-L-cysteinyl-, cyclic (1→14)-thioether PD-1/PD-L1 Inhibitor 3 USP/EP/BP PD-1/PD-L1-IN 3 PD-1/PD-L1 Inhibitor 3 TFA 1629654-95-0 C89H126N24O18S