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LOC-14

LOC-14 structure

CAS No.: 877963-94-5

Chemical Name:: LOC-14

Synonyms: OC14;LOC-14;LOC14, ≥98%;LOC 14;LOC14;LOC 14,inhibit,LOC14,Inhibitor,LOC-14;2-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]methyl]-1,2-benzisothiazol-3(2H)-one;2-((4-(cyclopropanecarbonyl)piperazin-1-yl)methyl)benzo[d]isothiazol-3(2H)-one;1,2-Benzisothiazol-3(2H)-one, 2-[[4-(cyclopropylcarbonyl)-1-piperazinyl]methyl]-;2-[(4-cyclopropanecarbonylpiperazin-1-yl)methyl]-2,3-dihydro-1,2-benzothiazol-3-one

CBNumber:: CB14668146

Molecular Formula:: C16H19N3O2S

Molecular Weight:: 317.41

MDL Number:: MFCD07849042

MOL File:: 877963-94-5.mol

Last updated:2023-06-08 09:02:20

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LOC-14 Properties

Boiling point	528.5±60.0 °C(Predicted)
Density	1.390±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMF: 10mg/mL; DMF:PBS (pH 7.2) (1:1): 0.5mg/mL; DMSO: 3mg/mL; Ethanol: 3mg/mL; Ethanol:PBS (pH 7.2) (1:6): 0.14mg/mL
form	A crystalline solid
pka	6.16±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P264-P270-P301+P312-P330-P501

NFPA 704

	0
2		0

LOC-14 price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	17766	LOC14	877963-94-5	10mg	$93	2024-03-01	Buy
Cayman Chemical	17766	LOC14	877963-94-5	100mg	$684	2024-03-01	Buy
Cayman Chemical	17766	LOC14	877963-94-5	25mg	$208	2024-03-01	Buy
Cayman Chemical	17766	LOC14	877963-94-5	50mg	$388	2024-03-01	Buy
Tocris	5606	LOC14 ≥98%(HPLC)	877963-94-5	10	$151	2021-12-16	Buy

Product number	Packaging	Price	Buy
17766	10mg	$93	Buy
17766	100mg	$684	Buy
17766	25mg	$208	Buy
17766	50mg	$388	Buy
5606	10	$151	Buy

LOC-14 Chemical Properties,Uses,Production

Uses

LOC14 acts as a high affinity disulfide isomerase (PDI) modulator. Neuroprotective agent.

LOC-14 Preparation Products And Raw materials

Raw materials

Preparation Products

LOC-14 Suppliers

Global( 51)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	757984502@qq.com	China	892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4604	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4153	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
InvivoChem	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	58
Aladdin Scientific	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
Shanghai Lollane Biological Technology Co.,Ltd.	55
Shanghai EFE Biological Technology Co., Ltd.	58

2-[(4-cyclopropanecarbonylpiperazin-1-yl)methyl]-2,3-dihydro-1,2-benzothiazol-3-one 1,2-Benzisothiazol-3(2H)-one, 2-[[4-(cyclopropylcarbonyl)-1-piperazinyl]methyl]- 2-((4-(cyclopropanecarbonyl)piperazin-1-yl)methyl)benzo[d]isothiazol-3(2H)-one LOC14, ≥98% LOC 14;LOC14 2-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]methyl]-1,2-benzisothiazol-3(2H)-one LOC-14 OC14 LOC 14,inhibit,LOC14,Inhibitor,LOC-14 877963-94-5