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ChemicalBook >> CAS DataBase List >>9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]-

9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]-

9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- Structure
9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- structure
CAS No.
2342583-66-6
Chemical Name:
9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]-
Synonyms
inhibit,NCC-007,Inhibitor,NCC007,NCC 007,Casein Kinase;9-(1-Cyclopropylethyl)-N2-(2-(dimethylamino)ethyl)-N6-(3-(trifluoromethyl)benzyl)-9H-purine-2,6-diamine;9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]-
CBNumber:
CB18245224
Molecular Formula:
C22H28F3N7
Molecular Weight:
447.5
MDL Number:
MFCD32067989
MOL File:
2342583-66-6.mol
Last updated:2023-03-13 11:54:02
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9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- Properties

Boiling point 573.5±60.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
pka 9.02±0.28(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P305+P351+P338

9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0097017 NCC007 99.58% 2342583-66-6 5mg $100 2021-12-16 Buy
ChemScene CS-0097017 NCC007 99.58% 2342583-66-6 10mg $150 2021-12-16 Buy
ChemScene CS-0097017 NCC007 99.58% 2342583-66-6 25mg $250 2021-12-16 Buy
ChemScene CS-0097017 NCC007 99.58% 2342583-66-6 50mg $450 2021-12-16 Buy
ChemScene CS-0097017 NCC007 99.58% 2342583-66-6 100mg $750 2021-12-16 Buy
Product number Packaging Price Buy
CS-0097017 5mg $100 Buy
CS-0097017 10mg $150 Buy
CS-0097017 25mg $250 Buy
CS-0097017 50mg $450 Buy
CS-0097017 100mg $750 Buy

9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- Chemical Properties,Uses,Production

Biological Activity

NCC007 is a dual casein kinase Iα (CKIα) and delta (CKIδ) inhibitor with IC50 of 1.8 and 3.6 μM, respectively. It can be used for the study of mammalian circadian rhythms.

in vivo

NCC007 (5-15 mM, infused into the lateral ventricle) controls circadian rhythms through CKI inhibition.

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Animal Model: Adult C57BL/6J background male mice (8 weeks old)
Dosage: 5 , 15 mM
Administration: Infused into the lateral ventricle, constant dark condition
Result: Showed more period lengthening effect with 0.15 hours at 5 mM and 15 mM.

target

CKIα

1.8 μM (IC 50 )

CKIδ

3.6 μM (IC 50 )

9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- Suppliers

Global( 20)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 4604 58
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8011 62
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2993 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720 chaolaichem@foxmail.com China 9038 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12308 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 9946 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
ShangHai Biochempartner Co.,Ltd 62
Shanghai Rechem science Co., Ltd. 58
Shanghai SuperLan Chemcial Technique Centre 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
cjbscvictory 58
9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- 9-(1-Cyclopropylethyl)-N2-(2-(dimethylamino)ethyl)-N6-(3-(trifluoromethyl)benzyl)-9H-purine-2,6-diamine inhibit,NCC-007,Inhibitor,NCC007,NCC 007,Casein Kinase 2342583-66-6 C22H28F3N7