ChemicalBook >> CAS DataBase List >>1H-Pyrazole-4-carboxamide, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl-

1H-Pyrazole-4-carboxamide, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl-

1H-Pyrazole-4-carboxamide, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl- structure

CAS No.: 2364554-48-1

Chemical Name:: 1H-Pyrazole-4-carboxamide, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl-

Synonyms: CK-274;Aficamten;Aficamten(CK274);Aficamten (CK-3773274;(R)-N-(5-(5-Ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)-1-methyl-1H-pyrazole-4-carboxamide;1H-Pyrazole-4-carboxamide, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl-;CK3773274,CK-3773274,cardiac,CK-274,Myosin,cardiomyopathy,Inhibitor,CK 3773274,CK 274,hypertrophic,inhibit,Aficamten,CK274,HCM

CBNumber:: CB18366125

Molecular Formula:: C18H19N5O2

Molecular Weight:: 337.38

MDL Number:

MOL File:: 2364554-48-1.mol

Last updated:2023-09-04 15:51:00

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1H-Pyrazole-4-carboxamide, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl- Properties

Density	1.40±0.1 g/cm3(Predicted)
solubility	DMSO : 125 mg/mL (370.50 mM; Need ultrasonic)
form	A crystalline solid
pka	13.84±0.20(Predicted)
FDA UNII	B1I77MH6K1

1H-Pyrazole-4-carboxamide, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl- Chemical Properties,Uses,Production

Uses

Aficamten can be useful in the study of myosin modulation in cardiovascular medicine.

1H-Pyrazole-4-carboxamide, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrazole-4-carboxamide, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl- Suppliers

Global( 36)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Suzhou ARTK Medchem Co., Ltd.	+86-512-68323967 +86-18015559028	sales1@artkmedchem.com	China	39009	58
Suzhou Meidi Senuo Pharmaceutical Technology Co., Ltd.	13771642864	snhuyu_2008@126.com	China	1028	58
Bayee Biotech (Anqing) Co., Ltd.	0556-0556-5032306 18917961636	wtx@bayeebio.com	China	214	61
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3423	58
Hygeia (Chengdu) pharmaceutical technique Co., Ltd	028-84502008 13568869383	sales@hygeiapharm.com	China	294	55
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4153	55

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Nantong HI-FUTURE Biology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Suzhou ARTK Medchem Co., Ltd.	58
Suzhou Meidi Senuo Pharmaceutical Technology Co., Ltd.	58
Bayee Biotech (Anqing) Co., Ltd.	61
ShangHai Caerulum Pharma Discovery Co., Ltd.	58
Hygeia (Chengdu) pharmaceutical technique Co., Ltd	55
Shanghai Lollane Biological Technology Co.,Ltd.	55

1H-Pyrazole-4-carboxamide, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl- Spectrum

1H-Pyrazole-4-carboxamide, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl-(2364554-48-1)¹HNMR

1H-Pyrazole-4-carboxamide, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl- CK-274 Aficamten Aficamten (CK-3773274 CK3773274,CK-3773274,cardiac,CK-274,Myosin,cardiomyopathy,Inhibitor,CK 3773274,CK 274,hypertrophic,inhibit,Aficamten,CK274,HCM Aficamten(CK274) (R)-N-(5-(5-Ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)-1-methyl-1H-pyrazole-4-carboxamide 2364554-48-1