Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester

1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester

1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester Structure
1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester structure
CAS No.
1087243-14-8
Chemical Name:
1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester
Synonyms
GRL-0496;1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester;chloropyridyl,GRL-0496,3CLpro,inhibit,GRL0496,Inhibitor,SARS-CoV,GRL 0496,SARS coronavirus
CBNumber:
CB19039741
Molecular Formula:
C14H9ClN2O2
Molecular Weight:
272.69
MDL Number:
MFCD34471049
MOL File:
1087243-14-8.mol
Last updated:2023-05-18 11:31:15
Request For Quotation

1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester Properties

Boiling point 483.9±35.0 °C(Predicted)
Density 1.431±0.06 g/cm3(Predicted)
storage temp. -20°
solubility Soluble in DMSO (>30 mg/mL) and ethanol (>25 mg/mL)
pka 15.35±0.30(Predicted)
form solid
color White
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML3251 GRL-1720 ≥98% (HPLC) 1087243-14-8 5MG $69.2 2024-03-01 Buy
Sigma-Aldrich SML3251 GRL-1720 ≥98% (HPLC) 1087243-14-8 25MG $280 2024-03-01 Buy
Product number Packaging Price Buy
SML3251 5MG $69.2 Buy
SML3251 25MG $280 Buy

1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester Chemical Properties,Uses,Production

Description

GRL-0496 (1087243-14-8) is a potent (IC50?= 30 nM in cell culture assays) inhibitor of severe acute respiratory syndrome-coronavirus chymotrypsin-like protease (SARS-CoV 3CLpro).1

Definition

ChEBI: (5-Chloropyridin-3-yl) 1H-indole-4-carboxylate is an indolyl carboxylic acid. It has a role as an anticoronaviral agent.

References

1)????Ghosh?et al. (2008),?Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors;?Bioorg. Med. Chem.Lett,?18?5684

1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Shanghai Beckham Medical Technology Co., Ltd 021-13816613772 13816613772 huahero21@sina.com China 359 55
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24018 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 4191 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9180 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanghai Beckham Medical Technology Co., Ltd 55
TargetMol Chemicals Inc. 58
Nantong QuanYi Biotechnology Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
RD International Technology Co., Limited 58

1087243-14-8(1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester)Related Search:

Ibrutinib N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1) Volasertib (BI 6727) Tigecycline
1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester GRL-0496 chloropyridyl,GRL-0496,3CLpro,inhibit,GRL0496,Inhibitor,SARS-CoV,GRL 0496,SARS coronavirus 1087243-14-8