ChemicalBook >> CAS DataBase List >>HYDROXYFASUDIL MONOHYDROCHLORIDE
HYDROXYFASUDIL MONOHYDROCHLORIDE
- CAS No.
- 155558-32-0
- Chemical Name:
- HYDROXYFASUDIL MONOHYDROCHLORIDE
- Synonyms
- Fasudil Hydroxy;Hydroxyfasudil HCl;Fasudil Impurity 7 HCl;Hydroxyfasudil (HA-1100);Hydroxyfasudil HCl (HA1100);Hydroxyfasudil Hydrochloride;Hydroxyfasudil (HA-1100) HCl;HYDROXYFASUDIL MONOHYDROCHLORIDE;Hydroxyfasudil hydrochloride hydrate;HA 1100 hydrochloride (Hydroxyfasudil)
- CBNumber:
- CB1973040
- Molecular Formula:
- C14H18ClN3O3S
- Molecular Weight:
- 343.82902
- MDL Number:
- MFCD06411567
- MOL File:
- 155558-32-0.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
HYDROXYFASUDIL MONOHYDROCHLORIDE price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H4413 | Hydroxyfasudil hydrochloride hydrate ≥98% (HPLC), solid | 155558-32-0 | 5mg | $286 | 2024-03-01 | Buy |
| Sigma-Aldrich | 390602 | Hydroxyfasudil | 155558-32-0 | 2mg | $159 | 2024-03-01 | Buy |
| Cayman Chemical | 14413 | HA-1100 (hydrochloride) ≥98% | 155558-32-0 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 14413 | HA-1100 (hydrochloride) ≥98% | 155558-32-0 | 5mg | $116 | 2024-03-01 | Buy |
| Sigma-Aldrich | H4413 | Hydroxyfasudil hydrochloride hydrate ≥98% (HPLC), solid | 155558-32-0 | 25mg | $1080 | 2024-03-01 | Buy |
HYDROXYFASUDIL MONOHYDROCHLORIDE Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
A metabolite of Fasudil. A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Reported to inhibit the Rho kinase-mediated (ROCK) contraction both in vitro and in vivo.
General Description
A cell-permeable, hydroxylated metabolite of HA 1077 (Fasudil; Cat. No. 371970) that displays anti-anginal properties. Acts as an ATP-competitive and a reversible inhibitor of Rho-kinase (IC50 = 0.9 and 1.8 μM using a peptide and MLC as substrate, respectively) with ~100-fold greater selectivity over MLCK, MRCKβ, and PKC. Reported to inhibit the Rho kinase-mediated contraction both in vitro and in vivo.
Biochem/physiol Actions
Cell permeable: yes
storage
-20°C
HYDROXYFASUDIL MONOHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
HYDROXYFASUDIL MONOHYDROCHLORIDE Suppliers
Global( 99)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9634 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
155558-32-0(HYDROXYFASUDIL MONOHYDROCHLORIDE)Related Search:
5-Quinolinesulfonic acid, 2-methyl-
Fasudil Pyridine N-Oxide TFA Salt
1,4-ditosyl-1,4-diazepane
Fasudil diMer
Fasudil Impurity 6
Fasudil Impurity 13
Fasudil N-hydroxy iMpurity
1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol
quinoline-5-sulphonic acid
Fasudil Impurity
1of4
5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-1(2H)-isoquinolinone
Hydroxyfasudil Hydrochloride
1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine monohydrochloride
HYDROXYFASUDIL MONOHYDROCHLORIDE
Hydroxyfasudil hydrochloride hydrate,1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine hydrochloride hydrate
1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine hydrochloride hydrate
Hydroxyfasudil hydrochloride hydrate
Hydroxyfasudil (HA-1100)
HA-1100 HYDROCHLORIDE;HA 1100 HYDROCHLORIDE;HA1100 HYDROCHLORIDE
5-(1,4-diazepan-1-ylsulfonyl)-2h-isoquinolin-1-one
Hydroxyfasudil hydrochloride (HA-1100 hydrochloride)
Hydroxyfasudil - CAS 155558-32-0 - Calbiochem
Hydroxyfasudil HCl
Hydroxyfasudil (HA-1100) HCl
1(2H)-Isoquinolinone, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1)
Fasudil Impurity 7 HCl
Fasudil Hydroxy
5-((1,4-diazepan-1-yl)sulfonyl)isoquinolin-1-ol hydrochloride
5-[(1,4-Diazepan-1-yl)sulfonyl]isoquinolin-1(2H)-one Hydrochloride
Hydroxyfasudil HCl (HA1100)
5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one,hydrochloride
HA-1100,ROCK,Hydroxyfasudil Hydrochloride,Hydroxyfasudil,Rho-associated kinase,HA 1100,inhibit,HA1100,Rho-kinase,Rho-associated protein kinase,ROK,Inhibitor
Hydroxyfasudil hydrochloride hydrate Hydroxyfasudil hydrochloride
HA 1100 hydrochloride (Hydroxyfasudil)
155558-32-0
C14H17N3O3SHCl
Various Metabolites and Impurities
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals