Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)-

2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)-

2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- Structure
2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- structure
CAS No.
1008671-38-2
Chemical Name:
2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)-
Synonyms
KCNQ1 activator-1;N-(4-(4-Methoxyphenyl)thiazol-2-yl)-1-(phenylsulfonyl)piperidine-2-carboxamide;N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-(phenylsulfonyl)piperidine-3-carboxamide;2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)-;1-(benzenesulfonyl)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperidine-2-carboxamide
CBNumber:
CB210697207
Molecular Formula:
C22H23N3O4S2
Molecular Weight:
457.57
MDL Number:
MOL File:
1008671-38-2.mol
Last updated:2023-05-21 10:59:17
Request For Quotation

2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- Properties

Density 1.364±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 250 mg/mL (546.36 mM; Need ultrasonic)
pka 8.37±0.70(Predicted)

2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- Chemical Properties,Uses,Production

Biological Activity

KCNQ1 activator-1 (compound 3) is a potent activator of KCNQ1 channel. KCNQ1 activator-1 has the potential for the research of long QT syndrome (LQTS)[1].

References

[1]. Mattmann ME, et al. Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator. Bioorg Med Chem Lett. 2012;22(18):5936-5941.

2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9767 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
Jingmo (Xiamen) Biotechnology Co., Ltd 13621943973 13515979683 sales@jamxmpharmatech.com China 1079 58
Hefei Mokai Pharmaceutical Technology Co., Ltd 18130062233 3362556465@qq.com China 8000 58
Bide Pharmatech Ltd. 400-1647117 15221909166 product02@bidepharm.com China 63720 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 market@aladdin-e.com China 48467 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Shanghai Chaolan Chemical Technology Center 58
DC Chemicals 58
Jingmo (Xiamen) Biotechnology Co., Ltd 58
Hefei Mokai Pharmaceutical Technology Co., Ltd 58
Bide Pharmatech Ltd. 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-(phenylsulfonyl)piperidine-3-carboxamide KCNQ1 activator-1 N-(4-(4-Methoxyphenyl)thiazol-2-yl)-1-(phenylsulfonyl)piperidine-2-carboxamide 1-(benzenesulfonyl)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperidine-2-carboxamide 1008671-38-2