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MI389
- CAS No.
- 2222635-92-7
- Chemical Name:
- MI389
- Synonyms
- MI389;MI 389;MI-389;MI 389,MI389
- CBNumber:
- CB211075798
- Molecular Formula:
- C35H35FN6O6
- Molecular Weight:
- 654.7
- MDL Number:
- MOL File:
- 2222635-92-7.mol
Last updated:2023-05-21 10:59:17
MI389 Chemical Properties,Uses,Production
Biological Activity
MI-389 is a PROTAC translation termination factor GSPT1 degrader. MI-389 disrupts a target that is a shared dependency in different AML and ALL cell lines, and that MI-389 action is dependent on the CRL4CRBN E3 ligase[1].
References
[1]. Ishoey M, et al. Translation Termination Factor GSPT1 Is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders. ACS Chem Biol. 2018;13(3):553-560.
MI389 Preparation Products And Raw materials
Raw materials
Preparation Products
MI389 Suppliers
Global( 2)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24018 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
MI 389
MI389
MI-389
MI 389,MI389
2222635-92-7