ChemicalBook >> CAS DataBase List >>3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
- CAS No.
- 218137-86-1
- Chemical Name:
- 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
- Synonyms
- C75;FAS inhibitor C75 (C-75;C75 >=98% (HPLC), powder;3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE;TRANS-4-CARBOXY-5-OCTYL-3-METHYLENEBUTYROLACTONE;3-Furancarboxylic acid, tetrahydro-4-methylene-2-octyl-5-oxo-;C75(4-Methylene-2-octyl-5-oxo-tetrahydro-furan-3-carboxylicacid);TRANS-TETRAHYDRO-3-METHYLENE-2-OXO-5-N-OCTYL-4-FURANCARBOXYLIC ACID
- CBNumber:
- CB2114165
- Molecular Formula:
- C14H22O4
- Molecular Weight:
- 254.32
- MDL Number:
- MFCD03265452
- MOL File:
- 218137-86-1.mol
- MSDS File:
- SDS
Last updated:2023-05-04 17:34:35
| Boiling point | 432.1±45.0 °C(Predicted) |
|---|---|
| Density | 1.08±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: 18 mg/mL |
| pka | 3.08±0.40(Predicted) |
| form | solid |
| color | off-white |
| FDA UNII | 8E9A8CTX2H |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| WGK Germany | 3 |
3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C5490 | C75 ≥98% (HPLC), powder | 218137-86-1 | 5mg | $345 | 2024-03-01 | Buy |
| Sigma-Aldrich | C5490 | C75 ≥98% (HPLC), powder | 218137-86-1 | 25mg | $1390 | 2024-03-01 | Buy |
| Tocris | 2489 | C75 ≥99%(HPLC) | 218137-86-1 | 10 | $227 | 2021-12-16 | Buy |
| Usbiological | 254848 | C 75 | 218137-86-1 | 10mg | $480 | 2021-12-16 | Buy |
| ChemScene | CS-3562 | C75 99.91% | 218137-86-1 | 50mg | $842 | 2021-12-16 | Buy |
3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Chemical Properties,Uses,Production
Uses
C75 has been used:
- as a fatty acid synthase (FASN) inhibitor to test its ability in the direct inhibition of FASN to attenuate mammosphere formation as compared to metformin
- as a pharmacological inhibitor to inhibit fatty acid synthesis in glioma stem cells (GSCs)
- as FAS inhibitor in the pre-treatment of Chang cells to inhibit lipogenesis and reverse the senescence induced by hydrogen peroxide
Definition
ChEBI: 4-methylene-2-octyl-5-oxo-3-oxolanecarboxylic acid is a gamma-lactone.
Biochem/physiol Actions
C75 helps to increase the cancer‐killing capability of ionizing radiation.
3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Preparation Products And Raw materials
Raw materials
Preparation Products
3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Suppliers
Global( 56)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2784 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3423 | 58 |
| Jiaxing Novartis Chemical Co., Ltd. | 18957373295 | China | 1580 | 58 | |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2993 | 58 |
218137-86-1(3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE)Related Search:
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3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
C75
C75(4-Methylene-2-octyl-5-oxo-tetrahydro-furan-3-carboxylicacid)
TRANS-4-CARBOXY-5-OCTYL-3-METHYLENEBUTYROLACTONE
TRANS-TETRAHYDRO-3-METHYLENE-2-OXO-5-N-OCTYL-4-FURANCARBOXYLIC ACID
FAS inhibitor C75
(C-75
3-Furancarboxylic acid, tetrahydro-4-methylene-2-octyl-5-oxo-
C75 >=98% (HPLC), powder
218137-86-1
Fatty acid synthase
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