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TAUROHYOCHOLATE

CAS No.
117997-17-8
Chemical Name:
TAUROHYOCHOLATE
Synonyms
TAUROHYOCHOLATE;Ethanesulfonic acid, 2-[[(3α,5β,6α,7α)-3,6,7-trihydroxy-24-oxocholan-24-yl]amino]-, monosodium salt
CBNumber:
CB21447602
Molecular Formula:
C26H45NO7S
Molecular Weight:
515.703
MDL Number:
MOL File:
117997-17-8.mol
Last updated:2023-05-21 10:59:17

TAUROHYOCHOLATE Properties

storage temp. Store at -20°C
solubility DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
form A lyophilized powder

TAUROHYOCHOLATE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22669 Taurohyocholic Acid (sodium salt) ≥95% 117997-17-8 5 mg $62 2024-03-01 Buy
Cayman Chemical 22669 Taurohyocholic Acid (sodium salt) ≥95% 117997-17-8 10 mg $109 2024-03-01 Buy
Cayman Chemical 22669 Taurohyocholic Acid (sodium salt) ≥95% 117997-17-8 25 mg $239 2024-03-01 Buy
Product number Packaging Price Buy
22669 5 mg $62 Buy
22669 10 mg $109 Buy
22669 25 mg $239 Buy

TAUROHYOCHOLATE Chemical Properties,Uses,Production

Biological Activity

Taurohyocholic acid (THCA) is a taurine-conjugated form of the porcine-specific primary bile acid hyocholic acid .1 THCA inhibits precipitation of cholesterol crystals by stabilizing cholesterol in the liquid-crystalline phase.2 It prevents cholestasis and cellular necrosis induced by taurolithocholic acid in isolated rat livers.3 THCA levels are increased in the urine of patients with hepatitis B-induced cirrhosis.4

References

1.Wahlstr?m, A., Sayin, S.I., Marschall, H.-I., et al.Intestinal crosstalk between bile acids and microbiota and its impact on host metabolismCell Metab.24(1)41-50(2016) 2.Juste, C., Catala, I., Henry, R., et al.Influence of bile salt molecular species on cholesterol crystallization from supersaturated model bilesBiochim. Biophys. Acta.1254(1)89-97(1995) 3.Scholmerich, J., Kitamura, S., Baumgartner, U., et al.Taurohyocholate, taurocholate, and tauroursodeoxycholate but not tauroursocholate and taurodehydrocholate counteract effects of taurolithocholate in rat liverRes. Exp. Med. (Berl.)190(2)121-129(1990) 4.Wang, X., Xie, G., Zhao, A., et al.Serum bile acids are associated with pathological progression of hepatitis B-induced cirrhosisJ. Proteome Res.15(4)1126-1134(2016)

TAUROHYOCHOLATE Preparation Products And Raw materials

Raw materials

Preparation Products

TAUROHYOCHOLATE Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
HX Pharmaceutical technology co., LTD 15671363360 494267389@qq.com China 2380 58
Jiangsu Duoyang Bioengineering Technology Co., Ltd 15161148838 2234255617@qq.com China 922 58
TAUROHYOCHOLATE Ethanesulfonic acid, 2-[[(3α,5β,6α,7α)-3,6,7-trihydroxy-24-oxocholan-24-yl]amino]-, monosodium salt 117997-17-8