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(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone

CAS No.
13084-70-3
Chemical Name:
(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone
Synonyms
Gitingensine;(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone;Pregn-5-en-18-oic acid, 3-amino-20-hydroxy-, γ-lactone, (3α,20S)-
CBNumber:
CB22228170
Molecular Formula:
C21H31NO2
Molecular Weight:
329.48
MDL Number:
MOL File:
13084-70-3.mol
Last updated:2023-05-04 17:34:32

(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone Properties

Melting point 160°C

(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone Chemical Properties,Uses,Production

Description

Gitingensine is a steroidal alkaloid which occurs in Kibatalia gitingensis, being found mainly in the leaves. It is optically active with a specific rotation of [α]31D - 65° (CHCI3). The hydrochloride has m.p. 281°C; [α]23D - 59.8° (CHCI3) and is more readily obtainable in the pure form than the free base. Deamination of the alkaloid by diazotization gives the deamino derivative, m.p. 235°C. The amino group may be methylated to yield the N-methyl compound, m.p. 223-4°C but the base cannot be methylated further.

Definition

ChEBI: Gitingensine is a steroid. It has a role as a metabolite.

References

Anguilar-Santos, Philipp. J. Sci., 94, 217 (1965)

(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone Preparation Products And Raw materials

Raw materials

Preparation Products

(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone Gitingensine Pregn-5-en-18-oic acid, 3-amino-20-hydroxy-, γ-lactone, (3α,20S)- 13084-70-3