Methyl 4-chloropicolinate
- CAS No.
- 24484-93-3
- Chemical Name:
- Methyl 4-chloropicolinate
- Synonyms
- 4-CHLORO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER;METHYL 4-CHLOROPYRIDINE-2-CARBOXYLATE;4-chloropicolinate;EOS-62380;IFLAB-BB F2108-0101;oro-2-pyridinecarboxyL;Methyl 4-chloropicolite;METHYL 4-CHLOROPICOLINATE;4-chloropyridine-2-formate;Methyl 4-Chloro-2-picolinate
- CBNumber:
- CB2224066
- Molecular Formula:
- C7H6ClNO2
- Molecular Weight:
- 171.58
- MDL Number:
- MFCD04116183
- MOL File:
- 24484-93-3.mol
- MSDS File:
- SDS
Melting point | 50-52 |
---|---|
Boiling point | 105-111 °C(Press: 2-3 Torr) |
Density | 1.294±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Solid |
pka | -0.25±0.10(Predicted) |
color | Off-White to Beige |
InChI | InChI=1S/C7H6ClNO2/c1-11-7(10)6-4-5(8)2-3-9-6/h2-4H,1H3 |
InChIKey | VTENWIPSWAMPKI-UHFFFAOYSA-N |
SMILES | C1(C(OC)=O)=NC=CC(Cl)=C1 |
CAS DataBase Reference | 24484-93-3(CAS DataBase Reference) |
Methyl 4-chloropicolinate price More Price(35)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | ADE000348 | 4-Chloro-pyridine-2-carboxylic acid methyl ester Aldrich | 24484-93-3 | 1g | $209 | 2024-03-01 | Buy |
TCI Chemical | M1832 | Methyl 4-Chloro-2-pyridinecarboxylate >98.0%(GC)(T) | 24484-93-3 | 1g | $20 | 2024-03-01 | Buy |
TCI Chemical | M1832 | Methyl 4-Chloro-2-pyridinecarboxylate >98.0%(GC)(T) | 24484-93-3 | 5g | $38 | 2024-03-01 | Buy |
TRC | M294455 | Methyl4-Chloropicolinate | 24484-93-3 | 1g | $60 | 2021-12-16 | Buy |
Usbiological | M3396-85 | Methyl 4-Chloropicolinate | 24484-93-3 | 1g | $333 | 2021-12-16 | Buy |
Methyl 4-chloropicolinate Chemical Properties,Uses,Production
Chemical Properties
Brown Solid
Uses
Methyl 4-Chloropicolinate (cas# 24484-93-3) is a compound useful in organic synthesis.
Production Methods
The starting material 2-picolinic acid was treated with SOCl2 to generate 4-chloropicolinoyl chloride, and then esterification with MeOH resulted in the formation of methyl 4-chloropicolinate.
Synthesis Reference(s)
Synthetic Communications, 26, p. 2017, 1996 DOI: 10.1080/00397919608003557
Synthesis
To a suspension of 4-chloropyridine-2-carboxylic acid (4.5 g, 29.0 mmol) in methylene chloride (120 mL) was added oxalyl chloride (3.0 mL, 1.2 eq) under Ar2. The reaction was cooled to 0° C., and 500 uL of DMF was added. A large amount of gas was generated in situ. The reaction was stirred at room temperature for 1.5 h and then concentrated. Dry MeOH (50 mL) was added to the crude acyl chloride residue. The reaction was stirred at room temperature for 0.5 h, then quenched with NaHCO3 (5%) to neutral, extracted with EtOAc, and washed with brine. The combined organics were dried over MgSO4, filtered, and concentrated in vacuo to give 5.0 g of a crude solid, which was triturated with 5% EtOAc/hexane to give Methyl 4-chloropicolinate as a light yellow solid (4.5 g, 90%).
Methyl 4-chloropicolinate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Wuhan BJM Pharm Inc | +86-027-5234-1919 +8613545198479 | sales03@benjaminpharmchem.com | China | 671 | 58 |
Jinan Dexinjia Bio&Tech Co., Ltd | +86-0531-82375893 +86-15553111391 | sales@jndxj.com | China | 1201 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 18225 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | forrest.lee@dakenchem.com | China | 15956 | 58 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2141 | 58 |
View Lastest Price from Methyl 4-chloropicolinate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-05-17 | Methyl 4-chloropicolinate
24484-93-3
|
US $170.00-150.00 / kg | 100kg | 99.99% | 100Tons | Hebei Dangtong Import and export Co LTD | ||
2024-01-02 | Methyl 4-chloropicolinate
24484-93-3
|
US $200.00-1.00 / KG | 1KG | 99%, 99.5% Sublimated | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | ||
2023-09-14 | Methyl 4-chloropicolinate
24484-93-3
|
US $100.00 / bag | 1bag | 99 | 5000 | Hebei Fengqiang Trading Co., LTD |
- Methyl 4-chloropicolinate
24484-93-3
- US $170.00-150.00 / kg
- 99.99%
- Hebei Dangtong Import and export Co LTD
- Methyl 4-chloropicolinate
24484-93-3
- US $200.00-1.00 / KG
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
- Methyl 4-chloropicolinate
24484-93-3
- US $100.00 / bag
- 99
- Hebei Fengqiang Trading Co., LTD