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trans-(-)-4-(4-Fluorophenyl)-1-methyl-3-[(4-toluenesulfonyloxy)methyl]piperidine

CAS No.
317323-77-6
Chemical Name:
trans-(-)-4-(4-Fluorophenyl)-1-methyl-3-[(4-toluenesulfonyloxy)methyl]piperidine
Synonyms
Paroxol Tosylate;Paroxetine Impurity 19;Paroxetine impurities782;((3S,4R)-4-phenylpiperidin-3-yl)methanol;(3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol Tosylate;Trans-(-)-4-(4Fluorophenyl)-1-methyl-3-[(4-toluenesulfonylox)methyl]piperidine;(-)-TRANS-4-(4-FLUOROPHENYL)-1-METHYL-3-[(4-TOLUENESULFONYLOXY)METHYL]PIPERIDINE;((3S,4R)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl)methyl 4-methylbenzenesulfote;3-PIPERIDINEMETHANOL,4-(4-FLUOROPHENYL)-1-METHYL-,4-METHYLBENZENESULFONATE(ESTER);((3S,4R)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl)methyl 4- methylbenzenesulfonate
CBNumber:
CB2254681
Molecular Formula:
C20H24FNO3S
Molecular Weight:
377.47
MDL Number:
MFCD08460097
MOL File:
317323-77-6.mol
MSDS File:
SDS
Last updated:2023-07-21 08:27:57

trans-(-)-4-(4-Fluorophenyl)-1-methyl-3-[(4-toluenesulfonyloxy)methyl]piperidine Properties

Melting point 117-118°C
Boiling point 496.2±45.0 °C(Predicted)
Density 1.195±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
form Solid
pka 8.23±0.20(Predicted)
color White to Off-White

SAFETY

Risk and Safety Statements

trans-(-)-4-(4-Fluorophenyl)-1-methyl-3-[(4-toluenesulfonyloxy)methyl]piperidine price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P205850 ParoxolTosylate 317323-77-6 10mg $90 2021-12-16 Buy
American Custom Chemicals Corporation APN0000004 (-)-TRANS-4-(4-FLUOROPHENYL)-1-METHYL-3-[(4-TOLUENESULFONYLOXY)METHYL]PIPERIDINE 95.00% 317323-77-6 25MG $529 2021-12-16 Buy
American Custom Chemicals Corporation APN0000004 (-)-TRANS-4-(4-FLUOROPHENYL)-1-METHYL-3-[(4-TOLUENESULFONYLOXY)METHYL]PIPERIDINE 95.00% 317323-77-6 250MG $2001.04 2021-12-16 Buy
Product number Packaging Price Buy
P205850 10mg $90 Buy
APN0000004 25MG $529 Buy
APN0000004 250MG $2001.04 Buy

trans-(-)-4-(4-Fluorophenyl)-1-methyl-3-[(4-toluenesulfonyloxy)methyl]piperidine Chemical Properties,Uses,Production

Chemical Properties

Brown Solid

Uses

Piperidine derivative intermediate for paroxetin preparation.

98-59-9
105812-81-5
317323-77-6
Synthesis of trans-(-)-4-(4-Fluorophenyl)-1-methyl-3-[(4-toluenesulfonyloxy)methyl]piperidine from Tosyl chloride and (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine

trans-(-)-4-(4-Fluorophenyl)-1-methyl-3-[(4-toluenesulfonyloxy)methyl]piperidine Preparation Products And Raw materials

Raw materials

Preparation Products

trans-(-)-4-(4-Fluorophenyl)-1-methyl-3-[(4-toluenesulfonyloxy)methyl]piperidine Suppliers

Global( 43)Suppliers
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CONIER CHEM AND PHARMA LIMITED
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Career Henan Chemica Co
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Hangzhou Huarong Pharm Co., Ltd.
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GIHI CHEMICALS CO.,LIMITED
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J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Beijing Comparison Pharmaceutical Technology Co., Ltd 010-52878169 15701683040 sales@bjcomparison.com China 4701 58
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632 sales@reading-chemicals.com China 15185 58
Shijiazhuang yaoBo Pharmaceutical Co., Ltd. 15633056635 2880679888@qq.com China 2740 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55936 58
3-PIPERIDINEMETHANOL, 4-(4-FLUOROPHENYL)-1-METHYL-, 4-METHYLBENZENESULFONATE (ESTER), (3S,4R)- (-)-TRANS-4-(4-FLUOROPHENYL)-1-METHYL-3-[(4-TOLUENESULFONYLOXY)METHYL]PIPERIDINE Trans-(-)-4-(4Fluorophenyl)-1-methyl-3-[(4-toluenesulfonylox)methyl]piperidine 3-PIPERIDINEMETHANOL,4-(4-FLUOROPHENYL)-1-METHYL-,4-METHYLBENZENESULFONATE(ESTER) 3-Piperidinemethanol, 4-(4-fluorophenyl)-1-methyl-, 3-(4-methylbenzenesulfonate), (3S,4R)- (3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol 3-(4-Methylbenzenesulfonate) (3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol Tosylate Paroxol Tosylate ((3S,4R)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl)methyl 4-methylbenzenesulfote ((3S,4R)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl)methyl 4- methylbenzenesulfonate Paroxetine Impurity 19 ((3S,4R)-4-phenylpiperidin-3-yl)methanol Paroxetine impurities782 317323-77-6 C20H24FNO3S Aromatics Chiral Reagents Heterocycles Sulfur & Selenium Compounds API intermediates