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ChemicalBook >> CAS DataBase List >>BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)-

BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)-

BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)- Structure
BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)- structure
CAS No.
866772-52-3
Chemical Name:
BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)-
Synonyms
LBX192;NVP-LBX192;NVP-LBX-192;NVP-LBX 192;(R)-3-cyclopentyl-N-(5-methoxy-thiazolo[5,4-b]pyridin-2-yl)-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionamide;(2R)-3-cyclopentyl-N-(5-methoxy-[1,3]thiazolo[5,4-b]pyridin-2-yl)-2-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]propanamide;BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)-
CBNumber:
CB22627427
Molecular Formula:
C26H33N5O4S2
Molecular Weight:
543.7
MDL Number:
MFCD18782674
MOL File:
866772-52-3.mol
Last updated:2023-03-31 09:12:58
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BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)- Properties

Density 1.340±0.06 g/cm3(Predicted)
pka 10.73±0.43(Predicted)

BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation CCH0012913 (ALPHAR)-ALPHA-(CYCLOPENTYLMETHYL)-N-(5-METHOXYTHIAZOLO-[5,4-B]PYRIDIN-2-YL)-4-[(4-METHYL-1-PIPERAZINYL)SULFONYL]BENZENEACETAMIDE 95.00% 866772-52-3 5MG $495.8 2021-12-16 Buy
Product number Packaging Price Buy
CCH0012913 5MG $495.8 Buy

BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)- Chemical Properties,Uses,Production

Description

LBX192, also known as NVP-LBX192, is a Liver Targeted Glucokinase Activator. LBX192 activated the GK enzyme in vitro at low nM concentrations and significantly reduced glucose levels during an oral glucose tolerance test in normal as well as diabetic mice. A GK activator has the promise of potentially affecting both the beta-cell of the pancreas, by improving glucose sensitive insulin secretion, as well as the liver, by reducing uncontrolled glucose output and restoring post prandial glucose uptake and storage as glycogen.

BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)- Preparation Products And Raw materials

Raw materials

Preparation Products

BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)- Suppliers

Global( 3)Suppliers
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TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
BOC Sciences -- info@bocsci.com USA 0 65
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24018 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
BOC Sciences 65
TargetMol Chemicals Inc. 58
BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)- (2R)-3-cyclopentyl-N-(5-methoxy-[1,3]thiazolo[5,4-b]pyridin-2-yl)-2-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]propanamide LBX192 (R)-3-cyclopentyl-N-(5-methoxy-thiazolo[5,4-b]pyridin-2-yl)-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionamide NVP-LBX 192 NVP-LBX192 NVP-LBX-192 866772-52-3 C26H33N5O4S2