XL-647
- CAS No.
- 651031-01-5
- Chemical Name:
- XL-647
- Synonyms
- CS-197;4-Quinazolinamine, N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-[[(3aa,5a,6aa)-octahydro- 2-met;7-{[(3aR,6aS)-2-Methyl-octahydrocyclopenta[c]pyrrol-5-yl]methoxy}-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine;N-(3,4-Dichloro-2-fluorophenyl)-6-methoxy-7-[[(3aα,5α,6aα)-octahydro-2-methylcyclopenta[c]pyrrol-5-yl]methoxy]-4-quinazolinamine;4-Quinazolinamine, N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-[[(3aα,5α,6aα)-octahydro-2-methylcyclopenta[c]pyrrol-5-yl]methoxy]-
- CBNumber:
- CB22650876
- Molecular Formula:
- C24H25Cl2FN4O2
- Molecular Weight:
- 491.39
- MDL Number:
- MFCD22124889
- MOL File:
- 651031-01-5.mol
XL-647 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | KIN0001437 | N-(3,4-DICHLORO-2-FLUORO PHENYL)-6-METHOXY-7-(((3AR,6AS)-2-METHYL OCTA HYDRO CYCLOPENTA[C]PYRROL-5-YL)-METHOXY)-QUINAZOLIN-4-AMINE 95.00% | 651031-01-5 | 5MG | $863.94 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001437 | N-(3,4-DICHLORO-2-FLUORO PHENYL)-6-METHOXY-7-(((3AR,6AS)-2-METHYL OCTA HYDRO CYCLOPENTA[C]PYRROL-5-YL)-METHOXY)-QUINAZOLIN-4-AMINE 95.00% | 651031-01-5 | 10MG | $1042.97 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001437 | N-(3,4-DICHLORO-2-FLUORO PHENYL)-6-METHOXY-7-(((3AR,6AS)-2-METHYL OCTA HYDRO CYCLOPENTA[C]PYRROL-5-YL)-METHOXY)-QUINAZOLIN-4-AMINE 95.00% | 651031-01-5 | 50MG | $1988.91 | 2021-12-16 | Buy |
| Matrix Scientific | 143814 | 4-Quinazolinamine | 651031-01-5 | 1g | $4070 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001437 | N-(3,4-DICHLORO-2-FLUORO PHENYL)-6-METHOXY-7-(((3AR,6AS)-2-METHYL OCTA HYDRO CYCLOPENTA[C]PYRROL-5-YL)-METHOXY)-QUINAZOLIN-4-AMINE 95.00% | 651031-01-5 | 250MG | $4297.65 | 2021-12-16 | Buy |
XL-647 Chemical Properties,Uses,Production
Uses
N-(3,4-Dichloro-2-fluorophenyl)-6-methoxy-7-[[(3aα,5α,6aα)-octahydro-2-methylcyclopenta[c]pyrrol-5-yl]methoxy]-4-quinazolinamine is an isomer of XL 647 (X746318) is a potent and selective EGFR phosphorylation inhibitor.
Uses
XL647 is a novel spectrum-selective kinase inhibitor for EGFR, ErbB2, KDR, Flt-4 and EphB4 with IC50 of 0.3 nM, 16 nM, 1.5 nM, 8.7 nM and 1.4 nM, respectively.
XL-647 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 9)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Trio PharmaTech Co., Ltd. | +86 (531) 88811783 | sales@trio-pharmatech.com (International market) | China | 1856 | 62 |
| NCE Biomedical Co.,Ltd. | 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 | China | 1494 | 55 | |
| Raw material medicin reagent co.,Ltd | sales@njromanme.com | China | 4534 | 58 | |
| Wuhan FengyaoTonghui Chemical Products Co., Ltd. | 027-87466105 15377573527 | 2678564200@qq.com | China | 17997 | 58 |
| Cckinase, Inc. | +1 (732)236-3202 | sales@cckinase.com | United States | 2738 | 58 |
| Jinan ponder chemical co. LTD | 0531-0000 | thinklifescience@163.com | China | 19690 | 58 |
| Jiangsu yize medical technology co. LTD | 18550739526 | 3394205705@qq.com | China | 9018 | 58 |
| Chunchuang (Wuhan) Technology Co., Ltd | 15342225168 | yutianchun2007@126.com | China | 10008 | 58 |
4-Quinazolinamine, N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-[[(3aa,5a,6aa)-octahydro- 2-met
CS-197
4-Quinazolinamine, N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-[[(3aα,5α,6aα)-octahydro-2-methylcyclopenta[c]pyrrol-5-yl]methoxy]-
N-(3,4-Dichloro-2-fluorophenyl)-6-methoxy-7-[[(3aα,5α,6aα)-octahydro-2-methylcyclopenta[c]pyrrol-5-yl]methoxy]-4-quinazolinamine
7-{[(3aR,6aS)-2-Methyl-octahydrocyclopenta[c]pyrrol-5-yl]methoxy}-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine
651031-01-5
C24H19Cl2FN4O2