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JNK inhibitor

JNK inhibitor Structure
JNK inhibitor structure
CAS No.
1408064-71-0
Chemical Name:
JNK inhibitor
Synonyms
CS-2418;JNK-IN-7;JNK inhibitor;JNK inhibitor 7;JNK Inhibitor VII;JNK-IN-7 Only for R&D;Inhibitor,JNK,inhibit,JNK IN 7,JNKIN7;3-(4-(Dimethylamino)but-2-enamido)-N-(4-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide;(E)-3-(4-(dimethylamino)but-2-enamido)-N-(4-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide;3-[[4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]-N-[4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide
CBNumber:
CB22666644
Molecular Formula:
C28H27N7O2
Molecular Weight:
493.56
MDL Number:
MFCD25976765
MOL File:
1408064-71-0.mol
Last updated:2023-09-20 16:43:00
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JNK inhibitor Properties

Density 1.301±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility ≥24.7 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form solid
pka 13.34±0.70(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315
Precautionary statements  P301+P312-P302+P352-P305+P351+P338
HS Code  2933998090
NFPA 704
0
2 0

JNK inhibitor price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 28831 JNK Inhibitor VII 1408064-71-0 1mg $121 2024-03-01 Buy
Cayman Chemical 28831 JNK Inhibitor VII 1408064-71-0 10mg $961 2024-03-01 Buy
Cayman Chemical 28831 JNK Inhibitor VII 1408064-71-0 5mg $543 2024-03-01 Buy
Cayman Chemical 28831 JNK Inhibitor VII 1408064-71-0 25mg $1802 2024-03-01 Buy
ChemScene CS-1554 JNK-IN-7 98.41% 1408064-71-0 100mg $1906 2021-12-16 Buy
Product number Packaging Price Buy
28831 1mg $121 Buy
28831 10mg $961 Buy
28831 5mg $543 Buy
28831 25mg $1802 Buy
CS-1554 100mg $1906 Buy

JNK inhibitor Chemical Properties,Uses,Production

Description

JNK inhibitor VII is a potent and non-selective inhibitor of JNKs (IC50s = 1.54, 1.99, and 0.75 nM for JNK1, -2, and -3, respectively). It inhibits phosphorylation of c-Jun in HeLa and A375 cells (EC50s = 130 and 244 nM, respectively).

Uses

JNK Inhibitor IX is a potent and selective inhibitor of JNK2 and JNK3. Neuroresearch & Neuroprotective Product.

References

[1]. zhang t, inesta-vaquera f, niepel m et al. discovery of potent and selective covalent inhibitors of jnk. chem biol. 2012 jan 27;19(1):140-54.
[2]. goh et, arthur js, cheung pc et al. identification of the protein kinases that activate the e3 ubiquitin ligase pellino 1 in the innate immune system. biochem j. 2012 jan 1;441(1):339-46.

JNK inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

JNK inhibitor Suppliers

Global( 70)Suppliers
Supplier Tel Email Country ProdList Advantage
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894 shawn@hirisunpharm.com CHINA 9923 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12382 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
LEAP CHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 24738 58
Coresyn Pharmatech Co., Ltd. 		+86-571-86626709 +86-18157142896 cbc@coresyn.com China 9991 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
PT CHEM GROUP LIMITED 		+86-85511178 +86-85511178 peter68@ptchemgroup.com China 35453 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 50002 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Supplier Advantage
Hefei Hirisun Pharmatech Co., Ltd 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
sgtlifesciences pvt ltd 		58
InvivoChem 		58
LEAP CHEM CO., LTD. 		58
Coresyn Pharmatech Co., Ltd. 		58
TargetMol Chemicals Inc. 		58
PT CHEM GROUP LIMITED 		58
GIHI CHEMICALS CO.,LIMITED 		58
Aladdin Scientific 		58

JNK inhibitor Spectrum

JNK inhibitor(1408064-71-0)1HNMR
3-[[4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]-N-[4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide JNK-IN-7 JNK inhibitor CS-2418 JNK inhibitor 7 Benzamide, 3-[[4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-N-[4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]- JNK-IN-7 Only for R&D (E)-3-(4-(dimethylamino)but-2-enamido)-N-(4-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide 3-(4-(Dimethylamino)but-2-enamido)-N-(4-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide Inhibitor,JNK,inhibit,JNK IN 7,JNKIN7 JNK Inhibitor VII 1408064-71-0 MAPK