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DAP-81

DAP-81 structure

CAS No.: 794466-17-4

Chemical Name:: DAP-81

Synonyms: DAP-81;Acetamide, N-[4-[[4-[(2-benzoylphenyl)amino]-5-nitro-2-pyrimidinyl]amino]phenyl]-

CBNumber:: CB22731043

Molecular Formula:: C25H20N6O4

Molecular Weight:: 468.46

MDL Number:: MFCD32173672

MOL File:: 794466-17-4.mol

Last updated:2023-03-31 09:12:57

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DAP-81 Chemical Properties,Uses,Production

Description

DAP-81 is a diaminopyrimidine derivative that targets PLKs, destabilizing kinetochore microtubules. Other spindle tubules are stabilized, resulting in monopolar mitotic spindles. In vitro, DAP-81 inhibits Plk1 at an IC50 of 0.9 nM. DAP-81 is currently in ongoing preclinical evaluations.

DAP-81 Preparation Products And Raw materials

Raw materials

Preparation Products

DAP-81 Suppliers

Global( 6)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Hangzhou ChangCun Biotechnology Co., Ltd.	0571-; 13567100326	158848739@qq.com	China	108	50
ShangHai Biochempartner Co.,Ltd	17754423994 17754423994	2853530910@QQ.com	China	8011	62
Tianjin Kaifu Pharmaceutical Technology Co., Ltd.	18081075745	chemflowtech@sina.com	China	1886	58
Chunchuang (Wuhan) Technology Co., Ltd	15342225168	yutianchun2007@126.com	China	10001	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.com	China	24246	58

Supplier	Advantage
BOC Sciences	58
Hangzhou ChangCun Biotechnology Co., Ltd.	50
ShangHai Biochempartner Co.,Ltd	62
Tianjin Kaifu Pharmaceutical Technology Co., Ltd.	58
Chunchuang (Wuhan) Technology Co., Ltd	58
TargetMol Chemicals Inc.	58

DAP-81 Acetamide, N-[4-[[4-[(2-benzoylphenyl)amino]-5-nitro-2-pyrimidinyl]amino]phenyl]- 794466-17-4