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GSK5959

GSK5959 Structure
GSK5959 structure
CAS No.
901245-65-6
Chemical Name:
GSK5959
Synonyms
CS-1636;GSK5959;BRPF1-IN-3;GSK-5959;GSK5959;N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide;Benzamide, N-[2,3-dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxy-;BRPF3,GSK5959,bromodomain,Inhibitor,inhibit,BRD1,BRPF1,Epigenetic Reader Domain,GSK-5959,GSK 5959,BRPF2,epigenetics
CBNumber:
CB23040788
Molecular Formula:
C22H26N4O3
Molecular Weight:
394.47
MDL Number:
MFCD14744183
MOL File:
901245-65-6.mol
Last updated:2023-06-30 15:45:59
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GSK5959 Properties

Boiling point 527.3±50.0 °C(Predicted)
Density 1.263±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 13 mg/mL (32.96 mM; Need ultrasonic and warming)
form Powder
pka 13.06±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

GSK5959 price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 18123 GSK5959 ≥98% 901245-65-6 1mg $32 2024-03-01 Buy
Cayman Chemical 18123 GSK5959 ≥98% 901245-65-6 5mg $100 2024-03-01 Buy
Cayman Chemical 18123 GSK5959 ≥98% 901245-65-6 10mg $184 2024-03-01 Buy
Cayman Chemical 18123 GSK5959 ≥98% 901245-65-6 25mg $381 2024-03-01 Buy
Tocris 5385 GSK5959 ≥99%(HPLC) 901245-65-6 10 $159 2021-12-16 Buy
Product number Packaging Price Buy
18123 1mg $32 Buy
18123 5mg $100 Buy
18123 10mg $184 Buy
18123 25mg $381 Buy
5385 10 $159 Buy

GSK5959 Chemical Properties,Uses,Production

Description

GSK 5959 exhibits >100-fold selectivity for BRPF1 (IC50 = 80 nM) over a panel of 35 other bromodomains, including BRPF2/3 and BET family bromodomains. Inhibits BRPF1 interaction with histone H3.3, which is involved in the epigenetic regulation of gene expression and have been implicated in human cancer.

Uses

GSK5959 is as elective BRPF1 bromodomain inhibitor.

storage

Store at +4°C

GSK5959 Preparation Products And Raw materials

Raw materials

Preparation Products

GSK5959 Suppliers

Global( 65)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32715 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Nanjing Doge Biomedical Technology Co., Ltd 		+86-25-58227606 +86-15305155328 sales@dogechemical.com China 4128 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42057 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
InvivoChem 		58
Nanjing Doge Biomedical Technology Co., Ltd 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
LEAPCHEM CO., LTD. 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58

GSK5959 Spectrum

GSK5959(901245-65-6)1HNMR

901245-65-6(GSK5959)Related Search:

GSK8612 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol 1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone GSK8612 GSK6853
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid GSK620 GSK591 ROR gamma-t-IN-1 GSK872

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GSK5959 Benzamide, N-[2,3-dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxy- CS-1636 GSK-5959;GSK5959 N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide BRPF1-IN-3 BRPF3,GSK5959,bromodomain,Inhibitor,inhibit,BRD1,BRPF1,Epigenetic Reader Domain,GSK-5959,GSK 5959,BRPF2,epigenetics 901245-65-6 Inhibitors