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2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE

CAS No.
92505-84-5
Chemical Name:
2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE
Synonyms
HO-(CH2CH2O)3-NH2 HCl;Amino-PEG3-alcohol HCl;NH2-PEG3 (hydrochloride);2-[(2-aminoethoxy)ethoxy]ethanol hydrochloride;2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE;2-(2-(2-Aminoethoxy)ethoxy)ethan-1-ol hydrochloride;Ethanol, 2-[2-(2-aminoethoxy)ethoxy]-, hydrochloride
CBNumber:
CB23838536
Molecular Formula:
C6H16ClNO3
Molecular Weight:
185.64914
MDL Number:
MFCD28963473
MOL File:
92505-84-5.mol
MSDS File:
SDS
Last updated:2023-02-23 14:24:01

2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE Chemical Properties,Uses,Production

Biological Activity

NH2-PEG3 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE Suppliers

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2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE Ethanol, 2-[2-(2-aminoethoxy)ethoxy]-, hydrochloride Amino-PEG3-alcohol HCl NH2-PEG3 (hydrochloride) 2-[(2-aminoethoxy)ethoxy]ethanol hydrochloride HO-(CH2CH2O)3-NH2 HCl 2-(2-(2-Aminoethoxy)ethoxy)ethan-1-ol hydrochloride 92505-84-5