ChemicalBook >> CAS DataBase List >>PBD-150
PBD-150
- CAS No.
- 790663-33-1
- Chemical Name:
- PBD-150
- Synonyms
- PBD-150;1-(3-(1H-imidazol-1-yl)propyl)-3-(3,4-dimethoxyphenyl)thiourea;Thiourea, N-(3,4-dimethoxyphenyl)-N'-[3-(1H-imidazol-1-yl)propyl]-;Inhibitor,Amyloid-β,PBD150,Abeta,PBD-150,β-amyloid peptide,inhibit,PBD 150,Alzheimer
- CBNumber:
- CB24668330
- Molecular Formula:
- C15H20N4O2S
- Molecular Weight:
- 320.41
- MDL Number:
- MFCD32666996
- MOL File:
- 790663-33-1.mol
Last updated:2023-06-08 09:02:16
| Melting point | 160.0-161.0 °C(Solv: ethanol (64-17-5)) |
|---|---|
| Boiling point | 502.7±60.0 °C(Predicted) |
| Density | 1.22±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (25 mg/ml) or ethanol (25 mg/ml) |
| form | solid |
| pka | 12.29±0.70(Predicted) |
| color | White |
| Stability | Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| NFPA 704 |
|
PBD-150 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0069369 | PBD-150 98.00% | 790663-33-1 | 5mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-0069369 | PBD-150 98.00% | 790663-33-1 | 10mg | $275 | 2021-12-16 | Buy |
| ChemScene | CS-0069369 | PBD-150 98.00% | 790663-33-1 | 50mg | $750 | 2021-12-16 | Buy |
| DC Chemicals | DC11797 | PBD-150 >98% | 790663-33-1 | 100mg | $550 | 2021-12-16 | Buy |
PBD-150 Chemical Properties,Uses,Production
Description
PBD-150 (790663-33-1) is an inhibitor of human glutaminyl cyclase (IC50 = 60 nM).1 PBD-150 diminished Ab plaque formation and gliosis while improving memory in a mouse model with small amounts of Ab3(pE)-40/42.2
References
Buchholz et al. (2006), The first potent inhibitors for human glutaminyl cyclase: synthesis and structure-activity relationship; J. Med. Chem., 49 664 Schilling et al. (2008), Glutaminyl cyclase inhibition attenuates pyroglutamate Ab and Alzheimer’s disease-like pathology; Nat. Med., 14 1106
PBD-150 Preparation Products And Raw materials
Raw materials
Preparation Products
PBD-150 Suppliers
Global( 23)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| ChemShuttle, Inc. | 0510-83588313-802 18800520310; | sales@chemshuttle.com | China | 3062 | 62 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3501 | 55 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8011 | 62 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
790663-33-1(PBD-150)Related Search:
PBD-150
1-(3-(1H-imidazol-1-yl)propyl)-3-(3,4-dimethoxyphenyl)thiourea
Inhibitor,Amyloid-β,PBD150,Abeta,PBD-150,β-amyloid peptide,inhibit,PBD 150,Alzheimer
Thiourea, N-(3,4-dimethoxyphenyl)-N'-[3-(1H-imidazol-1-yl)propyl]-
790663-33-1