ChemicalBook >> CAS DataBase List >>MM-589 TFA salt
MM-589 TFA salt
- CAS No.
- 2097887-21-1
- Chemical Name:
- MM-589 TFA salt
- Synonyms
- MM-589 (TFA);MM-589 TFA salt;MM589 TFA,MM 589 TFA
- CBNumber:
- CB24675387
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD32689433
- MOL File:
- Mol file
Last updated:2024-01-25 15:49:39
MM-589 TFA salt Chemical Properties,Uses,Production
Biological Activity
MM-589 TFA is a potent inhibitor of WD repeat domain 5 (WDR5) and mixed lineage leukemia (MLL) protein-protein interactions. MM-MM-589 TFA binds WDR5 with an IC50 of 0.90 nM. IC50 for inhibition of MLL H3K4 methyltransferase activity is 12.7 nM.
in vitro
MM-589 TFA (0.01-10 μM, 4 days or 7 days) potently and selectively inhibits cell growth in human leukemia cell lines harboring MLL translocations.
Cell Viability Assay < table class="zh_use_1"> < tr>
| Cell Line: | MV4-11 and MOLM-13 cells |
| Concentration: | 0.01, 0.1, 1, 10 μM |
| Incubation Time: | 4 days or 7 days |
| Result: | Potently inhibited MV4-11 and MOLM-13 cell growth with IC 50 s of 0.25 and 0.21 μM, respectively. Had much weaker activity in the inhibition of cell growth of the HL-60 cell line with an IC 50 of 8.6 μM. |
target
IC50: 0.90 nM (WDR5), 12.7 nM (HMT)
Ki: <1 nM (WDR5)
MM-589 TFA salt Preparation Products And Raw materials
Raw materials
Preparation Products
MM-589 TFA salt Suppliers
Global( 19)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15185 | 58 |
| Nanjing Leon Biological Technology Co., Ltd. | 17705183659 | sales@njleonbiotech.com | China | 5503 | 55 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | eric@peptidego.com | China | 6347 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5132 | 58 |
| Wuxi Helen Biotechnology Co., Ltd., | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 14092 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 3689 | 58 |
View Lastest Price from MM-589 TFA salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-02 | MM-589 TFA
2097887-21-1
|
US $2.00 / kg | 1kg | 99% | 200kg | Wuhan Xinhao Biotechnology Co., Ltd |
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- MM-589 TFA
2097887-21-1
- US $2.00 / kg
- 99%
- Wuhan Xinhao Biotechnology Co., Ltd
MM-589 TFA salt
MM-589 (TFA)
MM589 TFA,MM 589 TFA
2097887-21-1