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(R)-1-((2R, 4R, SR)-3,3-difluoro-4-hydroxy (hydroxymethyl) tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one

(R)-1-((2R, 4R, SR)-3,3-difluoro-4-hydroxy (hydroxymethyl) tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one Structure
(R)-1-((2R, 4R, SR)-3,3-difluoro-4-hydroxy (hydroxymethyl) tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one structure
CAS No.
1141397-80-9
Chemical Name:
(R)-1-((2R, 4R, SR)-3,3-difluoro-4-hydroxy (hydroxymethyl) tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one
Synonyms
E 7727);Cedazuridine (E7727;Clascoterone Impurity 38;Uridine, 2'-deoxy-2',2'-difluoro-3,4,5,6-tetrahydro-, (4R)-;(R)-1-((2R, 4R, SR)-3,3-difluoro-4-hydroxy (hydroxymethyl) tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one
CBNumber:
CB24745473
Molecular Formula:
C9H14F2N2O5
Molecular Weight:
268.21
MDL Number:
MFCD32062663
MOL File:
1141397-80-9.mol
Last updated:2023-05-21 10:59:17
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(R)-1-((2R, 4R, SR)-3,3-difluoro-4-hydroxy (hydroxymethyl) tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one Properties

Boiling point 597.7±50.0 °C(Predicted)
Density 1?+-.0.1 g/cm3(Predicted)
storage temp. 4°C, protect from light
solubility DMSO : 50 mg/mL (186.42 mM; ultrasonic and warming and heat to 60°C)
pka 11.72±0.70(Predicted)
FDA UNII 39IS23Q1EW

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS07
Signal word  Warning
Hazard statements  H373-H341-H302+H332
Precautionary statements  P260-P314-P501-P201-P202-P281-P308+P313-P405-P501

(R)-1-((2R, 4R, SR)-3,3-difluoro-4-hydroxy (hydroxymethyl) tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one Chemical Properties,Uses,Production

(R)-1-((2R, 4R, SR)-3,3-difluoro-4-hydroxy (hydroxymethyl) tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one synthesis

1141397-48-9
1141397-80-9
Synthesis of (R)-1-((2R, 4R, SR)-3,3-difluoro-4-hydroxy (hydroxymethyl) tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one from Uridine, 2'-deoxy-2',2'-difluoro-3,4,5,6-tetrahydro-

(R)-1-((2R, 4R, SR)-3,3-difluoro-4-hydroxy (hydroxymethyl) tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-1-((2R, 4R, SR)-3,3-difluoro-4-hydroxy (hydroxymethyl) tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one Suppliers

Global( 35)Suppliers
Supplier Tel Email Country ProdList Advantage
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32715 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23556 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 4691 58
Shanghai Synmedia Chemical Co., Ltd. 021-38681880 13817889927 sales@synmedia-chem.com China 249 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3427 58
Beijing Qinling Mountains Pharmaceutical Co., Ltd. 010-61241352 18901327973 sales@qlmed.com China 518 58
Supplier Advantage
Nantong HI-FUTURE Biology Co., Ltd.
58
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
ANHUI WITOP BIOTECH CO., LTD 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
Shanghai Synmedia Chemical Co., Ltd. 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Beijing Qinling Mountains Pharmaceutical Co., Ltd. 58
(R)-1-((2R, 4R, SR)-3,3-difluoro-4-hydroxy (hydroxymethyl) tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one Cedazuridine (E7727 E 7727) Uridine, 2'-deoxy-2',2'-difluoro-3,4,5,6-tetrahydro-, (4R)- Clascoterone Impurity 38 1141397-80-9