ChemicalBook >> CAS DataBase List >>AST2818 mesylate
AST2818 mesylate
- CAS No.
- 2130958-55-1
- Chemical Name:
- AST2818 mesylate
- Synonyms
- Alflutinib mesylate;Furmonertinib;AST2818 mesylate;ASK120067 mesylate;Furmonertinib mesylate;Alflutinib methanesulfonate;Alflutinib mesylate (AST2818);Alflutinib (AST2818 mesylate);Alflutinib mesylate (Furmonertinib);N-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide methanesulfonate
- CBNumber:
- CB24797023
- Molecular Formula:
- C29H35F3N8O5S
- Molecular Weight:
- 664.71
- MDL Number:
- MFCD31746903
- MOL File:
- 2130958-55-1.mol
Last updated:2024-05-22 13:12:52
| storage temp. | Store at -20°C,unstable in solution, ready to use. |
|---|---|
| solubility | Chloroform: 10 mg/ml; DMF: slightly soluble; DMSO: slightly soluble |
| form | A crystalline solid |
| FDA UNII | Q09ZKD19V0 |
| NCI Drug Dictionary | alflutinib mesylate |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| NFPA 704 |
|
AST2818 mesylate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0067492 | AST2818mesylate 99.99% | 2130958-55-1 | 5mg | $200 | 2021-12-16 | Buy |
| ChemScene | CS-0067492 | AST2818mesylate 99.99% | 2130958-55-1 | 10mg | $300 | 2021-12-16 | Buy |
| ChemScene | CS-0067492 | AST2818mesylate 99.99% | 2130958-55-1 | 50mg | $850 | 2021-12-16 | Buy |
| ChemScene | CS-0067492 | AST2818mesylate 99.99% | 2130958-55-1 | 100mg | $1250 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573198 | Alflutinib mesylate (AST2818) | 2130958-55-1 | 100mg | $1283.5 | 2021-12-16 | Buy |
AST2818 mesylate Chemical Properties,Uses,Production
Description
Furmonertinib (formerly known as alflutinib) is another me-too third-generation EGFR TKI that has a pyridyl ring replacing the phenyl ring of osimertinib and a trifluoroethyl group replacing the methyl group (Fig. 4). This TKI, which was discovered and developed by Shanghai Allist Pharma, was approved in November 2019 by the NMPA of China for the second-line treatment of NSCLC with EGFR sensitive mutation and EGFR T790M drug-resistant mutation, and more recently as a first-line treatment for classical EGFR mutant NSCLC. In June 2022, furmonertinib was granted the Fast Track designation by the FDA in patients with advanced or metastatic NSCLC with activating EGFR or HER2 mutations, including exon 20 insertion mutations.
AST2818 mesylate Preparation Products And Raw materials
Raw materials
Preparation Products
AST2818 mesylate Suppliers
Global( 45)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9425 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 4604 | 58 |
| Shanghai Payne Pharmaceutical Technology Co.Ltd | 021-58123769 18678586262 | info@paynepharm.com | China | 1354 | 58 |
| Chuzhou KeMail Chemical Technology Co., Ltd | 0550-5196001 15000891977 | wj520wjxby@126.com | China | 1836 | 55 |
View Lastest Price from AST2818 mesylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-09-27 | AST2818 mesylate
2130958-55-1
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- AST2818 mesylate
2130958-55-1
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
N-[2-[[2-(Dimethylamino)ethyl]methylamino]-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-2-propenamide compd. with methanesulfonate (1:1)
AST2818 mesylate
Alflutinib mesylate (AST2818)
Alflutinib methanesulfonate
Alflutinib (AST2818 mesylate)
Alflutinib mesylate
Alflutinib mesylate (Furmonertinib)
Furmonertinib mesylate
cancer,Epidermal growth factor receptor,AST2818,esistant mutation,Alflutinib,Alflutinib mesylate,AST-2818,Furmonertinib,HER1,AST 2818,NSCLC,ErbB-1,Inhibitor,EGFR,T790M,inhibit
N-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide methanesulfonate
ASK120067 mesylate
Furmonertinib
2130958-55-1