ChemicalBook >> CAS DataBase List >>UNIL-088
UNIL-088
- CAS No.
- 473545-11-8
- Chemical Name:
- UNIL-088
- Synonyms
- UNIL-088;Cyclosporin A, 6-[(2S,3R,4R,6E)-3-[[N-[[1-(acetyloxy)ethoxy]carbonyl]-O-phosphono-L-seryl-N-methylglycyl]oxy]-4-methyl-2-(methylamino)-6-octenoic acid]-
- CBNumber:
- CB24919788
- Molecular Formula:
- C73H128N13O22P
- Molecular Weight:
- 1570.87
- MDL Number:
- MOL File:
- 473545-11-8.mol
Last updated:2023-03-31 09:12:58
UNIL-088 Chemical Properties,Uses,Production
Description
UNIL088 is a water-soluble prodrug of cyclosporine A (CsA) designed for topical ocular delivery. The pro-moiety is grafted via an ester function to CsA and the solubilizing group is a phosphate ion. UNIL-088 can be rapidly hydrolysed under physiological conditions, and can retain a long shelf-life in aqueous media. UNIL-088 is more stable at pH 5 than at pH 7 with conversion rate constant of 3.2 x 10(-3) and 26.0 x 10(-3)days(-1), respectively.
UNIL-088 Preparation Products And Raw materials
Raw materials
Preparation Products
UNIL-088 Suppliers
Global( 2)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1249 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Beijing Biocreative Technology Co., Ltd. | 58 |
UNIL-088
Cyclosporin A, 6-[(2S,3R,4R,6E)-3-[[N-[[1-(acetyloxy)ethoxy]carbonyl]-O-phosphono-L-seryl-N-methylglycyl]oxy]-4-methyl-2-(methylamino)-6-octenoic acid]-
473545-11-8