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KENDOMYCIN

CAS No.
183202-73-5
Chemical Name:
KENDOMYCIN
Synonyms
kendomycin from streptomyces violaceoruber;1,19:5,9-Diepoxybenzocyclooctadecen-3(5H)-one, 6,7,8,9,10,11,12,15,16,17,18,19-dodecahydro-4,7,19-trihydroxy-2,6,8,12,14,16,18-heptamethyl-, (5R,6R,7S,8R,9R,12S,13E,16S,18S,19S)-
CBNumber:
CB2503707
Molecular Formula:
C29H42O6
Molecular Weight:
486.64
MDL Number:
MFCD14635192
MOL File:
183202-73-5.mol
Last updated:2023-06-30 15:45:59

KENDOMYCIN Properties

Melting point 236-240℃
Boiling point 678.5±55.0 °C(Predicted)
Density 1.19±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility Soluble in DMSO
form solid
pka 8.53±0.70(Predicted)
color Yellow

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

KENDOMYCIN price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich K1513 Kendomycin from Streptomyces violaceoruber solid 183202-73-5 100μg $261 2023-01-07 Buy
Cayman Chemical 11037 Kendomycin ≥98% 183202-73-5 100μg $81 2024-03-01 Buy
Cayman Chemical 11037 Kendomycin ≥98% 183202-73-5 500μg $219 2024-03-01 Buy
TRC K162503 Kendomycin 183202-73-5 100μg $145 2021-12-16 Buy
Adipogen Life Sciences BVT-0001-C500 Kendomycin ≥98%(HPLC) 183202-73-5 500μg $140 2021-12-16 Buy
Product number Packaging Price Buy
K1513 100μg $261 Buy
11037 100μg $81 Buy
11037 500μg $219 Buy
K162503 100μg $145 Buy
BVT-0001-C500 500μg $140 Buy

KENDOMYCIN Chemical Properties,Uses,Production

Description

Kendomycin is a macrolide from Streptomyces which displays potent cytotoxicity against several carcinoma cell lines (GI50 < 100 nM). It also acts as an endothelin receptor antagonist and has antiosteoporotic activities. Certain effects are thought to be mediated through inhibition of proteasomal degradation of proteins.

Uses

Kendomycin is a broadly efficacious polyketide macrocycle antibiotic.

Uses

Kendomycin is an unusual macrocyclic metabolite containing a rare quinone methide group. Kendomycin is a potent antibacterial agent against Gram positive and Gram negative bacteria, including MRSA strains, also displaying antitumour activity. Kendomycin is a potent endothelin receptor agonist and demonstrates antiosteoporotic activity.

Definition

ChEBI: Kendomycin is a member of benzofurans.

storage

+4°C

KENDOMYCIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 23)Suppliers
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TargetMol Chemicals Inc.
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Aladdin Scientific
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Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3989 66
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Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4381 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55954 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
kendomycin from streptomyces violaceoruber 1,19:5,9-Diepoxybenzocyclooctadecen-3(5H)-one, 6,7,8,9,10,11,12,15,16,17,18,19-dodecahydro-4,7,19-trihydroxy-2,6,8,12,14,16,18-heptamethyl-, (5R,6R,7S,8R,9R,12S,13E,16S,18S,19S)- 183202-73-5 C29H42O6