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STM2457

STM2457 Structure
STM2457 structure
CAS No.
2499663-01-1
Chemical Name:
STM2457
Synonyms
STM2457;leukaemia,Apoptosis,cancer,STM-2457,autoimmune diseases,STM2457,inhibit,STM 2457,myeloid,Inhibitor;N-((6-(((Cyclohexylmethyl)amino)methyl)imidazo[1,2-a]pyridin-2-yl)methyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxamide;4H-Pyrido[1,2-a]pyrimidine-2-carboxamide, N-[[6-[[(cyclohexylmethyl)amino]methyl]imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxo-;4-Oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylic acid {6-[(cyclohexylmethyl-amino)-methyl]-imidazo[1,2-a]pyridin-2-ylmethyl}-amide;N - (6- (((cyclohexylmethyl) amino) methyl) imidazolo [1,2-a] pyridin-2-yl) methyl) -4-oxo-4H-pyridino [1,2-a] pyrimidin-2-formamide
CBNumber:
CB28670993
Molecular Formula:
C25H28N6O2
Molecular Weight:
444.53
MDL Number:
MFCD34368521
MOL File:
2499663-01-1.mol
Last updated:2023-05-21 10:59:17
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STM2457 Properties

Density 1.35±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 270 mg/mL
form A solid
pka 13.74±0.20(Predicted)

STM2457 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML3360 STM2457 ≥98% (HPLC) 2499663-01-1 5MG $86.5 2024-03-01 Buy
Sigma-Aldrich SML3360 STM2457 ≥98% (HPLC) 2499663-01-1 25MG $280 2024-03-01 Buy
DC Chemicals 028229 STM2457 2499663-01-1 003 $400 2021-12-16 Buy
DC Chemicals 028229 STM2457 2499663-01-1 002 $280 2021-12-16 Buy
Product number Packaging Price Buy
SML3360 5MG $86.5 Buy
SML3360 25MG $280 Buy
028229 003 $400 Buy
028229 002 $280 Buy

STM2457 Chemical Properties,Uses,Production

Definition

ChEBI: STM2457 is a secondary carboxamide resulting from the formal condensation of the carboxy group of 4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylic acid with the primary amino group of 1-[2-(aminomethyl)imidazo[1,2-a]pyridin-6-yl]-N-(cyclohexylmethyl)methanamine. It is a highly potent and selective first-in-class small molecule inhibitor of METTL3 (N6-adenosine-methyltransferase 70 kDa subunit) enzyme activity and exhibits anti-leukaemic activity. It has a role as an EC 2.1.1.348 (mRNA m6A methyltransferase) inhibitor, an antineoplastic agent and an apoptosis inducer. It is an imidazopyridine, a secondary carboxamide, a secondary amino compound and a pyridopyrimidine.

STM2457 Preparation Products And Raw materials

Raw materials

Preparation Products

STM2457 Suppliers

Global( 44)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Henan Alfa Chemical Co., Ltd 		+8618339805032 alfa4@alfachem.cn China 12975 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3136 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Jinan Jiuli Biotechnology Co. , Ltd. 2717893647 14768611851 486064515@qq.com China 1111 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
BOC Sciences 		58
Henan Alfa Chemical Co., Ltd 		58
Nextpeptide Inc 		58
InvivoChem 		58
Nantong HI-FUTURE Biology Co., Ltd. 		58
TargetMol Chemicals Inc. 		58
LEAPCHEM CO., LTD. 		58
Aladdin Scientific 		58
Jinan Jiuli Biotechnology Co. , Ltd. 58

STM2457 Spectrum

4H-Pyrido[1,2-a]pyrimidine-2-carboxamide, N-[[6-[[(cyclohexylmethyl)amino]methyl]imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxo-(2499663-01-1)1HNMR
4H-Pyrido[1,2-a]pyrimidine-2-carboxamide, N-[[6-[[(cyclohexylmethyl)amino]methyl]imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxo- 4-Oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylic acid {6-[(cyclohexylmethyl-amino)-methyl]-imidazo[1,2-a]pyridin-2-ylmethyl}-amide STM2457 leukaemia,Apoptosis,cancer,STM-2457,autoimmune diseases,STM2457,inhibit,STM 2457,myeloid,Inhibitor N-((6-(((Cyclohexylmethyl)amino)methyl)imidazo[1,2-a]pyridin-2-yl)methyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxamide N - (6- (((cyclohexylmethyl) amino) methyl) imidazolo [1,2-a] pyridin-2-yl) methyl) -4-oxo-4H-pyridino [1,2-a] pyrimidin-2-formamide 2499663-01-1