ChemicalBook >> CAS DataBase List >>4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

CAS No.
2271036-45-2
Chemical Name:
4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Synonyms
BUN36452;Poma-PEG2-N3;Pomalidomide-PEG2-C2-azide;4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;Pomalidomide 4' PEG2 azide?,inhibit,Pomalidomide 4'-PEG-2-azide?,Pomalidomide 4'PEG2azide?,Inhibitor,E3 Ligase Ligand-Linker Conjugates
CBNumber:
CB29441448
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD32903292
MOL File:
Mol file
Last updated:2024-04-01 18:08:31

4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Chemical Properties,Uses,Production

Biological Activity

Pomalidomide 4’-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

storage

Store at -20°C

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Preparation Products And Raw materials

Raw materials

Preparation Products

4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Suppliers

Global( 17)Suppliers
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TargetMol Chemicals Inc.
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Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2996 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4824 58
Shanghai SPAR pharmaceutical technology co., LTD 021000000 admin@jingshipharmatech.com China 10075 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1305 58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD 025-86755008 17751752005 hszhang@bestfluorodrug.com China 2358 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 caoy@chemextension.com China 3090 58
Zhengzhou convergence chemical co., LTD 0371-0371-55153829 18003835034 2853979819@qq.com China 8780 58
Hubei Kele Fine Chemical Co., Ltd 027-59101668 19945030958 2881924765@qq.com China 7977 58

View Lastest Price from 4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide-NH-PEG2-azide pictures 2024-04-02 Pomalidomide-NH-PEG2-azide
2271036-45-2
US $0.00 / mg 100mg >98.00% 100mg Xian confluore Biological Technology Co., Ltd.
4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione BUN36452 Pomalidomide 4' PEG2 azide?,inhibit,Pomalidomide 4'-PEG-2-azide?,Pomalidomide 4'PEG2azide?,Inhibitor,E3 Ligase Ligand-Linker Conjugates Pomalidomide-PEG2-C2-azide Poma-PEG2-N3 2271036-45-2