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Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]-

Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- structure

CAS No.: 1454902-97-6

Chemical Name:: Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]-

Synonyms: Elevenostat;N-hydroxy-4-((3-(2-methoxyphenyl)ureido)methyl)benzamide;Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]-;Histone deacetylases,Elevenostat,JB3-22,multiple myeloma,inhibit,HDAC11,Inhibitor,HDAC

CBNumber:: CB310614294

Molecular Formula:: C16H17N3O4

Molecular Weight:: 315.32

MDL Number:

MOL File:: 1454902-97-6.mol

Last updated:2023-05-21 10:59:17

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Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- Properties

Density	1.328±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 250 mg/mL (792.85 mM; Need ultrasonic)
pka	8.92±0.10(Predicted)

Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- Chemical Properties,Uses,Production

Biological Activity

Elevenostat (JB3-22) is a selective HDAC11 inhibitor (IC50=0.235 μM). Anti-multiple myeloma (MM) activity[1].

References

[1]. Huang J, et al. Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function. Sci Rep. 2017;7(1):8626. Published 2017 Aug 17. [2]. Mostofa A, et al. Plasma cell dependence on histone/protein deacetylase 11 reveals a therapeutic target in multiple myeloma. JCI Insight. 2021;6(24):e151713. Published 2021 Dec 22.

Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- Suppliers

Global( 12)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9767	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9414	58
Jingmo (Xiamen) Biotechnology Co., Ltd	13621943973 13515979683	sales@jamxmpharmatech.com	China	1079	58
Bide Pharmatech Ltd.	400-1647117 15221909166	product02@bidepharm.com	China	63720	58
InvivoChem	13549236410	sales@invivochem.cn	China	6713	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24018	58
Henan Alpha Chemical Co., Ltd.	0371-55013243 15324716602	2853979810@qq.com	China	9957	58
https://hanhongsci.com/	021-54306202 18917919676	info@hanhongsci.com	China	29989	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Shanghai Chaolan Chemical Technology Center	58
DC Chemicals	58
Jingmo (Xiamen) Biotechnology Co., Ltd	58
Bide Pharmatech Ltd.	58
InvivoChem	58
TargetMol Chemicals Inc.	58
Henan Alpha Chemical Co., Ltd.	58
https://hanhongsci.com/	58

Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- N-hydroxy-4-((3-(2-methoxyphenyl)ureido)methyl)benzamide Elevenostat Histone deacetylases,Elevenostat,JB3-22,multiple myeloma,inhibit,HDAC11,Inhibitor,HDAC 1454902-97-6