Tenidap
- CAS No.
- 120210-48-2
- Chemical Name:
- Tenidap
- Synonyms
- TENIDAP;AKOS 91367;TENIDAP USP/EP/BP;CP66248,CP-66248-2;5-Chloro-2，3-dihydro-2-oxo-3-(2-thenoyl)-1H-indole-1-carboxamide;(Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H- indole-1-carboxaMide;(3Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H-indole-1-carboxaMide;1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (3Z)-
- CBNumber:
- CB3121977
- Molecular Formula:
- C14H9ClN2O3S
- Molecular Weight:
- 320.75
- MDL Number:
- MFCD00865996
- MOL File:
- 120210-48-2.mol
- MSDS File:
- SDS
| Melting point | 230° (dec) |
|---|---|
| Boiling point | 538.1±60.0 °C(Predicted) |
| Density | 1.648±0.06 g/cm3(Predicted) |
| storage temp. | Store at +4°C |
| solubility | DMSO: soluble1mg/mL, clear (warmed) |
| form | powder |
| pka | 4.50±1.00(Predicted) |
| color | faint yellow to dark yellow |
| FDA UNII | 9K7CJ74ONH |
| ATC code | M01AX23 |
Tenidap price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PZ0196 | Tenidap ≥97% (HPLC) | 120210-48-2 | 5mg | $129 | 2024-03-01 | Buy |
| Sigma-Aldrich | PZ0196 | Tenidap ≥97% (HPLC) | 120210-48-2 | 25mg | $401 | 2024-03-01 | Buy |
| Cayman Chemical | 17413 | Tenidap ≥98% | 120210-48-2 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 17413 | Tenidap ≥98% | 120210-48-2 | 5mg | $70 | 2024-03-01 | Buy |
| Cayman Chemical | 17413 | Tenidap ≥98% | 120210-48-2 | 10mg | $122 | 2024-03-01 | Buy |
Tenidap Chemical Properties,Uses,Production
Uses
Anti-inflammatory (osteoarthritis and rheumatoid arthritis).
Uses
Tenidap is one of the nonsteroidal antiinflammatory drugs (NSAIDs). Tenidap is an NSAID that preferentially inhibits COX-1. Tenidap inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes.
Definition
ChEBI: Tenidap is a member of indoles, a member of ureas, a member of thiophenes and an organochlorine compound. It has a role as a non-steroidal anti-inflammatory drug and an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor.
Biological Activity
NSAID that preferentially inhibits COX-1 (IC 50 values are < 0.03, 1.2 and > 30 μ M for COX-1, COX-2 and 5-lipoxygenase respectively). Inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes. Opener of inward rectifying hK IR 2.3 channel (EC 50 = 402 nM).
storage
Store at +4°C
Mode of action
Tenidap is an anti-inflammatory agent developed by Pfizer with a unique structure that is different and distinguishable from NSAIDs. The mechanism of action of tenidap is that it has dual inhibitory effects on lipoxygenase and dioxygenase, and has antagonism on interleukin-1 (IL-1).
Tenidap Preparation Products And Raw materials
Tenidap Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28455 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 18958018566; | info@afinechem.com | China | 15377 | 58 |
| Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 992 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2127 | 70 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
View Lastest Price from Tenidap manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-07 | TENIDAP USP/EP/BP
120210-48-2
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
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- TENIDAP USP/EP/BP
120210-48-2
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited