4SC-201
- CAS No.
- 864814-88-0
- Chemical Name:
- 4SC-201
- Synonyms
- CS-304;RAS2410;4SC-201;ResMinostat;ResMinostat(4SC-201);ResMinostat (RAS2410);RESMINOSTAT; 4SC-201; RAS2410;4SC-201(resminostat,BYK408740);RAS2410;4SC-201;RAS 2410;RAS-2410;(E)-3-[1-[4-[(dimethylamino)methyl]phenyl]sulfonylpyrrol-3-yl]-N-hydroxyprop-2-enamide
- CBNumber:
- CB32582958
- Molecular Formula:
- C16H19N3O4S
- Molecular Weight:
- 349.4
- MDL Number:
- MFCD18633257
- MOL File:
- 864814-88-0.mol
| Density | 1.28±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Powder |
| pka | 8.68±0.23(Predicted) |
| FDA UNII | 1578EUB98L |
| NCI Drug Dictionary | resminostat |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
4SC-201 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ApexBio Technology | A4108 | Resminostat(RAS2410) | 864814-88-0 | 5mg | $173 | 2021-12-16 | Buy |
| ApexBio Technology | A4108 | Resminostat(RAS2410) | 864814-88-0 | 10mg | $284 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611518 | Resminostat | 864814-88-0 | 100mg | $690.2 | 2021-12-16 | Buy |
| ApexBio Technology | A4108 | Resminostat(RAS2410) | 864814-88-0 | 50mg | $1010 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611518 | Resminostat | 864814-88-0 | 250mg | $1208.7 | 2021-12-16 | Buy |
4SC-201 Chemical Properties,Uses,Production
Uses
Resminostat is an oral histone deacetylase (HDAC) inhibitor. It inhibits proliferation and induces apoptosis in multiple myeloma (MM) cells.
Biological Activity
resminostat, also known as ras2410, is a potent inhibitor of histone deacetylase (hdac) classes i and ii (including hdac1, hdac3 and hdac6) with 50% inhibition concentration ic50 values ranging from 43 to 72 nmol/l. resminostate has the potential to be used for the treatment of multiple myeloma (mm) due to its ability to induce histone h4 hyperacetylation, and apoptosis (ic50 ranging from 2.5 to 3 μmol/l) in mm cells. recent study results have shown that, in mm cell lines, resminostat abrogates cell growth, suppresses proliferation and induce g0/g1 cell cycle arrest as well as interfering with akt signaling pathway by decreasing phosphorylation of 4e-bp1 and p70s6k.mandl-weber s, meinel fg, jankowsky r, oduncu f, schmidmaier r, baumann p. the novel inhibitor of histone deacetylase resminostat (ras2410) inhibits proliferation and induces apoptosis in multiple myeloma (mm) cells. br j haematol. 2010; 149(4):518-528.
4SC-201 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9991 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
View Lastest Price from 4SC-201 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-31 | Resminostat
864814-88-0
|
US $1.00 / KG | 1KG | Min98% HPLC | g/kg/ton | Career Henan Chemical Co |
-
- Resminostat
864814-88-0
- US $1.00 / KG
- Min98% HPLC
- Career Henan Chemical Co