ChemicalBook >> CAS DataBase List >>1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione structure

CAS No.: 114262-49-6

Chemical Name:: 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione

Synonyms: Sofosbuvir metabolites GS331007;Sofosbuvir Methylarabinosyl Impurity;Hydroxyuridine/Sofosbuvir Impurity 12;1-β-D-Arabinofuranosyluracil-2-C-methyl;1-(2'-C-methyl-β-D-arabinofuranosyl)uracil;1-(2-C-Methyl-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione;2,4(1H,3H)-Pyrimidinedione, 1-(2-C-methyl-β-D-arabinofuranosyl)-;1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione

CBNumber:: CB32715875

Molecular Formula:: C10H14N2O6

Molecular Weight:: 258.23

MDL Number:

MOL File:: 114262-49-6.mol

MSDS File:: SDS

Request For Quotation

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Properties

Melting point	132-135 °C
Density	1.572±0.06 g/cm3(Predicted)
pka	9.39±0.10(Predicted)

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A764005	1-β-D-Arabinofuranosyluracil-2-C-methyl	114262-49-6	25mg	$165	2021-12-16	Buy
ChemScene	CS-M2827	1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione	114262-49-6	5mg	$1500	2021-12-16	Buy

Product number	Packaging	Price	Buy
A764005	25mg	$165	Buy
CS-M2827	5mg	$1500	Buy

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Chemical Properties,Uses,Production

Uses

1-β-D-Arabinofuranosyluracil-2-C-methyl is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Preparation Products And Raw materials

Raw materials

Preparation Products

PSI7409

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Suppliers

Global( 31)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
Xi'an MC Biotech, Co., Ltd.	029-89275612 +8618991951683	mcbio_sales@163.com	China	2255	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19743	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Guangzhou PI PI Biotech Inc	+86-020-81716320 +86-13602409664	Sales@pipitech.com	China	3635	55
Artis Chemistry (Shanghai) Co. Ltd.	86-21-60936353		China	336	58
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7553	61
Nanjing XiZe Biotechnology CO., Ltd.	025-58362220 15250997978	1511893459@qq.com	China	7726	55
SPIRO PHARMA		eric_feng1954@126.com	China	9254	55

Supplier	Advantage
ANHUI WITOP BIOTECH CO., LTD	58
Xi'an MC Biotech, Co., Ltd.	58
BOC Sciences	58
sgtlifesciences pvt ltd	58
LEAPCHEM CO., LTD.	58
Guangzhou PI PI Biotech Inc	55
Artis Chemistry (Shanghai) Co. Ltd.	58
Haoyuan Chemexpress Co., Ltd.	61
Nanjing XiZe Biotechnology CO., Ltd.	55
SPIRO PHARMA	55

114262-49-6(1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione)Related Search:

Sofosbuvir SofosBuvir Impurity 14 SofosBuvir Impurity 52 PSI-7976 2'-deoxy-2'-fluoro-2'-C-methyluridine

SofosBuvir Impurity 50 (S)-methyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate Sofosbuvir Impurity23 Sofosbuvir impurity I Sofosbuvir IMpurity C 1337482-15-1

SofosBuvir Impurity 39 1-((2S,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione sofosBuvir impurity 1 Sofosbuvir Impurity25 Sofosbuvir Impurity 5

Sofosbuvir metabolites D-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-Methyl-P-phenyl-5'-uridylyl]-, 1-Methylethyl ester SofosBuvir impurity 44

1of4

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Sofosbuvir metabolites GS331007 1-(2-C-Methyl-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione 1-(2'-C-methyl-β-D-arabinofuranosyl)uracil Hydroxyuridine/Sofosbuvir Impurity 12 2,4(1H,3H)-Pyrimidinedione, 1-(2-C-methyl-β-D-arabinofuranosyl)- Sofosbuvir Methylarabinosyl Impurity 1-β-D-Arabinofuranosyluracil-2-C-methyl 114262-49-6