ChemicalBook >> CAS DataBase List >>Ripasudil Hydrochloride
Ripasudil Hydrochloride
- CAS No.
- 223644-02-8
- Chemical Name:
- Ripasudil Hydrochloride
- Synonyms
- Glanatec;Ripasudil Hydrochloride;(2S)-1-[(4-Fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-1H-1,4-diazepine monohydrochloride
- CBNumber:
- CB32738175
- Molecular Formula:
- C15H19ClFN3O2S
- Molecular Weight:
- 359.8466632
- MDL Number:
- MOL File:
- 223644-02-8.mol
- MSDS File:
- SDS
Last updated:2023-06-03 08:28:36
| Melting point | 258-259 °C (decomp) |
|---|---|
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Sparingly) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| FDA UNII | 3CZ0FF0XJO |
Ripasudil Hydrochloride Chemical Properties,Uses,Production
Uses
Ripasudil (Glanatec TM, Kowa Pharmaceutical), a close derivative of fasudil, is another Rho kinase inhibitor approved in Japan at the end of 2014 for the treatment of glaucoma and ocular hypertensionwhen other therapeutic agents are not effective or cannot be administered. Additionally, ripasudil has been tested in diabetic retinopathy clinical trials and shown to promote corneal endothelial cell proliferation, endothelium regeneration, and wound healing.
Uses
Ripasudil Hydrochloride Dihydrate is a derivative of fasudil and a rho kinase inhibitor (1,2). It is used for the treatment of glaucoma and ocular hypertension.
Synthesis of Ripasudil Hydrochloride from 4-Fluoro-5-isoquinolinesulfonyl chloride hydrochloride (1:1) and (S)-1-BOC-2-METHYL-[1,4]DIAZEPANE
Ripasudil Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Ripasudil Hydrochloride Suppliers
Global( 6)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21687 | 55 |
| Suzhou Haiheng Biological Pharmaceutical Co., Ltd. | 0512-65045967 15365387483 | sales@haihengpharm.com | China | 94 | 55 |
| Pharmacodia (Beijing) Co.,Ltd | +86-400-851-9921 | sales@pharmacodia.com | China | 2317 | 55 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19105 | 58 |
| Wuhan Topule | +86-02787215551 +86-19945035818 | 2936752263@qq.com | China | 8284 | 58 |
| Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 | czbjpharma@126.com | China | 18488 | 58 |
223644-02-8(Ripasudil Hydrochloride)Related Search:
Ripasudil Hydrochloride
(2S)-1-[(4-Fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-1H-1,4-diazepine monohydrochloride
Glanatec
223644-02-8
C15H18FN3O2SHCl