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4'-CHLOROACETANILIDE

4'-CHLOROACETANILIDE structure

CAS No.: 539-03-7

Chemical Name:: 4'-CHLOROACETANILIDE

Synonyms: NSC 444;NSC 40563;4-Chloroacetan;PARACETAMOL RC J;4-CHLORACETANILIDE;p-Chloroacetanilid;P-CHLOROACETANILIDE;4-CHLOROACETANILIDE;4'-CHLOROACETANILIDE;ACETAMINOPHENE IMP J

CBNumber:: CB3377826

Molecular Formula:: C8H8ClNO

Molecular Weight:: 169.61

MDL Number:: MFCD00000612

MOL File:: 539-03-7.mol

MSDS File:: SDS

Last updated:2024-04-25 13:42:50

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4'-CHLOROACETANILIDE Properties

Melting point	176-178 °C(lit.)
Boiling point	333 °C
Density	1,385 g/cm³
refractive index	1.5670 (estimate)
Flash point	333°C
storage temp.	2-8°C
solubility	dioxane: 50 mg/mL hot, clear
pka	14.25±0.70(Predicted)
form	Crystalline Powder
color	White or grayish-beige
Water Solubility	Insoluble in water.
Merck	14,2111
BRN	509638
CAS DataBase Reference	539-03-7(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	6I0LI34G5J
EPA Substance Registry System	4-Chloroacetanilide (539-03-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

RTECS

AE1001000

TSCA

Yes

HS Code

29242990

NFPA 704

	0
1		0

4'-CHLOROACETANILIDE price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	Y0001945	Paracetamol impurity J European Pharmacopoeia (EP) Reference Standard	539-03-7	Y0001945	$152	2024-03-01	Buy
Sigma-Aldrich	8.41480	4-Chloroacetanilide for synthesis	539-03-7	50g	$65.3	2024-03-01	Buy
Sigma-Aldrich	8.41480	4-Chloroacetanilide for synthesis	539-03-7	250g	$299	2024-03-01	Buy
Sigma-Aldrich	158631	4′-Chloroacetanilide 97%	539-03-7	5g	$43.5	2024-03-01	Buy
Sigma-Aldrich	1003100	Acetaminophen Related Compound J United States Pharmacopeia (USP) Reference Standard	539-03-7	50mg	$1380	2024-03-01	Buy

Product number	Packaging	Price	Buy
Y0001945	Y0001945	$152	Buy
8.41480	50g	$65.3	Buy
8.41480	250g	$299	Buy
158631	5g	$43.5	Buy
1003100	50mg	$1380	Buy

4'-CHLOROACETANILIDE Chemical Properties,Uses,Production

Chemical Properties

white or greyish-beige crystalline powder

Uses

4'-Chloroacetanilide is used in pharmaceutical preparations, using PGC column. And also used in the synthesis of alprazolam.

Definition

ChEBI: Acetamide substituted on nitrogen by a para-chlorophenyl group.

Synthesis Reference(s)

Tetrahedron, 52, p. 8863, 1996 DOI: 10.1016/0040-4020(96)00433-4

General Description

4′-Chloroacetanilide is the main impurity present in acetaminophen and has been quantitated by new high-performance liquid chromatography method using a mixed-mode reversed-phase/cation exchange stationary phase.

Purification Methods

Crystallise the anilide from EtOH or aqueous EtOH. [Beilstein 12 IV 1178.]

4'-CHLOROACETANILIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N-(2-AMINO-4-CHLOROPHENYL)ANTHRANILIC ACID Ethanone,1-(2-amino-5-chlorophenyl)- 2,6-DICHLORO-1,4-BENZOQUINONE 2'-Chloroacetanilide 5-Chloroorthanilic acid

N-(4-CHLOROPHENYL)-N-ETHYLFORMAMIDE

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4'-CHLOROACETANILIDE Suppliers

Global( 340)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12467	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8822	58
Shanghai Worldyang Chemical Co.,Ltd.	,+86-21-56795779; +8613651600618	sales@worldyachem.com	China	879	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Hubei Jusheng Technology Co.,Ltd.	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Shanghai Worldyang Chemical Co.,Ltd.	58
Standardpharm Co. Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
SIMAGCHEM CORP	58

View Lastest Price from 4'-CHLOROACETANILIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-25	4'-CHLOROACETANILIDE 539-03-7	US $10.00 / kg	1kg	99.8%	10000ton	Ouhuang Engineering Materials (Hubei) Co., Ltd
2023-08-31	4'-CHLOROACETANILIDE 539-03-7	US $100.00 / bag	1bag	99	5000	Hebei Fengqiang Trading Co., LTD
2023-07-05	4'-CHLOROACETANILIDE 539-03-7	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd

4'-CHLOROACETANILIDE
539-03-7
US $10.00 / kg
99.8%
Ouhuang Engineering Materials (Hubei) Co., Ltd

4'-CHLOROACETANILIDE
539-03-7
US $100.00 / bag
99
Hebei Fengqiang Trading Co., LTD

4'-CHLOROACETANILIDE
539-03-7
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

4'-CHLOROACETANILIDE Spectrum

4'-CHLOROACETANILIDE(539-03-7)MS 4'-CHLOROACETANILIDE(539-03-7)¹HNMR 4'-CHLOROACETANILIDE(539-03-7)IR1 4'-CHLOROACETANILIDE(539-03-7)IR2 4'-CHLOROACETANILIDE(539-03-7)Raman

539-03-7(4'-CHLOROACETANILIDE)Related Search:

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ACETIC ACID 4-CHLOROANILIDE ACETAMINOPHEN IMPURITY J ACETAMINOPHENE IMP J 4'-CHLOROACETANILIDE 4-CHLOROACETANILIDE 4-CHLORACETANILIDE LABOTEST-BB LT00792311 P-CHLOROACETANILIDE N-(4-CHLORO-PHENYL)-ACETAMIDE P-ChloroAcetanilide-(AceticAcid-4-Chloroanilide,4-ChloroAcetanilide) P-ChloroAcetanilideGr-(AceticAcid-4-Chloroanilide,4-ChloroAcetanilide) P-ChloroAcetanilideGr 4''-CHLOROACETANILIDE, 98+% p-CHLOROACETANILIDE extrapure AR 4'-Chloroacetanilide,97% 4′-Chloroacetanilide,Acetic acid 4-chloroanilide NSC 40563 NSC 444 p-Chloroacetanilid AcetaMinophen IMpurity J (ParacetaMol IMpurity J) AcetaMinophen Related CoMpound J 4-Chloroacetan Acetaminophen Related Compound J (50 mg) (N-(4-chlorophenyl)acetamide) Paracetamol Impurity-J(EP/BP) 4’-chloro-acetanilid 4-chlorophenylethanamide Acetamide,N-(4-chlorophenyl)- Acetanilide, 4'-chloro- Acetic-4-chloroanilide Acet-p-chloroanilide amide,n(4-chlorophenyl)-aceticaci ethanamide,4-chlorophenyl- n-(4-chlorophenyl)-acetamid N-(p-Chlorophenyl)acetamide N-Acetyl-4-chloroaniline N-Acetyl-p-chloroaniline p-Chloroacetoanilide 4-Chloroacetanilide (Acetaminophen RCJ) Acetaminophen impurity 10 Paracetamol EP Impurity J Paracetamol Impurity 10(Paracetamol EP Impurity J) 4’-CHLOROACETANILIDE(Acetaminophen Related Compound J) paracetamol impurity J 4'-Chloroacetanilide > N-(4-Chlorophenyl)acetamide (4-Chlo 4-CHLOROACETANILIDE FOR SYNTHESIS Paracetamol(Acetaminophen) EP Impurity J Parachloroacetanilide 4-Chloroacetanilide/ Paracetamol Impurity-J Paracetamol Impurity-J/4-Chloroacetanilide Acetaminophen impurities1464 Acetaminophen EP Impurity J Acetaminophen Related Compound J (R00310) p-Chloroacetanilide, GR 99%+ p-Chloroacetanilide extrapure AR, ExiPlus, Multi-Compendial, 99% Paracetamol EP Impurity JQ: What is Paracetamol EP Impurity J Q: What is the CAS Number of Paracetamol EP Impurity J Q: What is the storage condition of Paracetamol EP Impurity J Q: What are the applications of Paracetamol EP Impurity J Acetaminophen Related Compound J (N-(4-chlorophenyl)acetamide) (1003100) Acetaminophen USP Related Compound J