ChemicalBook >> CAS DataBase List >>LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)

LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)

CAS No.
27244-64-0
Chemical Name:
LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)
Synonyms
6-Hydroxy-L-DOPA;(2S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid;Topa;Levodopa Related CoMpound A;6-oh-dopa;Topaquinone;l-hydroxydopa;Hydroxy-L-dopa;l-6-hydroxydopa;6-Hydroxydopa, L-
CBNumber:
CB3501432
Molecular Formula:
C9H11NO5
Molecular Weight:
213.19
MDL Number:
MOL File:
27244-64-0.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Properties

Melting point >190°C (dec.)
Boiling point 515.2±38.0 °C(Predicted)
Density 1.606±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Aqueous Acid (Slightly, Sonicated), Water (Slightly, Heated, Sonicated)
pka 2.34±0.25(Predicted)
color Brown to Black
Stability Air Sensitive, Hygroscopic
FDA UNII 580PK2O48O

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315
Precautionary statements  P264-P270-P280-P301+P312+P330-P332+P313-P501
HS Code  2922504500

LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2095 Levodopa Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material 27244-64-0 100mg $593 2024-03-01 Buy
Sigma-Aldrich 1361010 Levadopa Related Compound A 27244-64-0 50mg $1490 2024-03-01 Buy
TRC H941725 6-Hydroxy-L-DOPA 27244-64-0 25mg $190 2021-12-16 Buy
TRC H941725 6-Hydroxy-L-DOPA 27244-64-0 250mg $1480 2021-12-16 Buy
Product number Packaging Price Buy
PHR2095 100mg $593 Buy
1361010 50mg $1490 Buy
H941725 25mg $190 Buy
H941725 250mg $1480 Buy

LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Chemical Properties,Uses,Production

Uses

6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.

Uses

6-Hydroxy-L-DOPA is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.

Definition

ChEBI: An L-alpha-amino acid that is L-dopa carrying an additional hydroxy substituent at position 6.

LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Preparation Products And Raw materials

Raw materials

Preparation Products

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2,5-dihydroxy-l-tyrosine 4,5-trihydroxyphenyl)-3-(l-alanin 6-oh-dopa l-2,4,5-trihydroxyphenylalanine l-6-hydroxydopa l-hydroxydopa LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) (S)-α-Amino-3,4,6-trihydroxybenzenepropanoic acid 2,4,5-Trihydroxy-L-phenylalanine Topaquinone 3-(3,4,6-Trihydroxyphenyl)-L-alanine Hydroxy-L-dopa 6-Hydroxy-L-DOPA (Levodopa Related CoMpound A) 3-(2,4,5-Trihydroxyphenyl)-L-alanine Levadopa Related Compound A Levodopa EP Impurity A 3-(3,4,6-Tirhydroxyphenyl)-alanine Levodopa Impurity 1 (Levodopa EP Impurity A) 6-Hydroxy L-DOPA (Levadopa Related Compound A) L-Tyrosine, 2,5-dihydroxy- (S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid Levodopa EP Impurity A/ Levodopa Related Compound A (2-Hydroxy Levodopa) 2-Hydroxy Levodopa Levodopa Related Compound A ((3-(2,4,5-Trihydroxyphenyl)-L-alanine) or (3-(3,4,6-Trihydroxyphenyl)a (1361010) Topa 6-Hydroxy-L-DOPA Levodopa Related CoMpound A (2S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid 6-Hydroxydopa, L- Levodopa EP Impurity A (Levodopa USP Related Compound A, 6-Hydroxy L-DOPA) Levodopa EP Impurity A Levodopa USP Related Compound A 27244-64-0 Amino Acids & Derivatives, Aromatics, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals