ChemicalBook >> CAS DataBase List >>Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-

Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-

Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- structure

CAS No.: 1904651-39-3

Chemical Name:: Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-

Synonyms: 7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-1,2,3,4-tetrahydroquinoline;7-(Difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1,2,3,4-tetrahydroquinoline;7-(dif luoromethyl)-6-(1 -methyl-1 H-pyrazol-4-y1)-1,2,3,4-tetrahydroquinoline;Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-

CBNumber:: CB38085848

Molecular Formula:: C14H15F2N3

Molecular Weight:: 263.29

MDL Number:

MOL File:: 1904651-39-3.mol

Last updated:2023-07-12 17:05:43

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Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- Properties

Boiling point	440.6±45.0 °C(Predicted)
Density	1.33±0.1 g/cm3(Predicted)
solubility	Dichloromethane; Ethyl Acetate; Methanol
pka	3.96±0.20(Predicted)
form	Solid
color	Off-White

Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- Chemical Properties,Uses,Production

Uses

7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-1,2,3,4-tetrahydroquinoline is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.

Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- Preparation Products And Raw materials

Raw materials

Preparation Products

Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- Suppliers

Global( 14)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Blocksynth Pharmaceutical Technology Co.,Ltd	0086-19817745290; +8619817745290	bd@blocksynth.com	China	5658	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19994	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Aikon International Limited	025-58851090 13611564524	lwan@aikonchem.com	China	15952	58
Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd.	15990591583		China	5565	58
Shanghai Kaiwei Chemical Technology Co., Ltd.	021-58461859 15821823057	service@aiviche.com	China	49323	58
Shanghai Ruoji Biomedical Technology Co., LTD	021-67103006 18117569361	wangyanyin@rujipharma.com	China	127	58
Wuhan Topule	+86-02787215551 +86-19945035818	2936752263@qq.com	China	8284	58
Hubei Kele Fine Chemical Co., Ltd	027-59101668 19945030958	2881924765@qq.com	China	7973	58
Wuhan Augda Biotechnology Co., Ltd	15071299552	262933239@qq.com	China	6637	58

Supplier	Advantage
Blocksynth Pharmaceutical Technology Co.,Ltd	58
Labnetwork lnc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Aikon International Limited	58
Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd.	58
Shanghai Kaiwei Chemical Technology Co., Ltd.	58
Shanghai Ruoji Biomedical Technology Co., LTD	58
Wuhan Topule	58
Hubei Kele Fine Chemical Co., Ltd	58
Wuhan Augda Biotechnology Co., Ltd	58

Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- 7-(Difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1,2,3,4-tetrahydroquinoline 7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-1,2,3,4-tetrahydroquinoline 7-(dif luoromethyl)-6-(1 -methyl-1 H-pyrazol-4-y1)-1,2,3,4-tetrahydroquinoline 1904651-39-3