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ChemicalBook >> CAS DataBase List >>Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester

Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester

Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester Structure
Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester structure
CAS No.
929551-91-7
Chemical Name:
Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester
Synonyms
AZ12441970;AZ-12441970;AZ 12441970;Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester
CBNumber:
CB38369827
Molecular Formula:
C27H41N7O4
Molecular Weight:
527.66
MDL Number:
MOL File:
929551-91-7.mol
Last updated:2023-03-31 09:12:58
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Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester Properties

Density 1.184±0.06 g/cm3(Predicted)
pka 10.25±0.20(Predicted)

Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester Chemical Properties,Uses,Production

Description

AZ12441970 is a potent toll-like receptor 7 agonist (TLR7 agonist). AZ12441970 showed efficacy in a mouse allergic airway model with minimal induction of systemic IFN-α, consistent with the low plasma levels of compound. AZ12441970 induced high levels of the notch ligands Dll1 and Dll4 mRNA, whereas immobilized DLL4 resulted in the suppression of IL-5 production.

Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester Suppliers

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Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester AZ 12441970 AZ12441970 AZ-12441970 929551-91-7 C27H41N7O4