4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol
![4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol Structure](CAS/GIF/17676-24-3.gif)
- CAS No.
- 17676-24-3
- Chemical Name:
- 4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol
- Synonyms
- C10628;hinokiresinol;trans-Hikiresil;cis-Hinokiresinol;(-)-Hinokiresinol;trans-Hinokiresinol;4-[1-[(E)-4-Hydroxystyryl]allyl]phenol;4,4'-[(E)-3-Vinyl-1-propene-1,3-diyl]bis[phenol];4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol;Phenol,4,4'-[(1E,3S)-3-ethenyl-1-propene-1,3-diyl]bis-
- CBNumber:
- CB41257863
- Molecular Formula:
- C17H16O2
- Molecular Weight:
- 252.31
- MDL Number:
- MOL File:
- 17676-24-3.mol
| Melting point | 69-71 °C(Solv: chloroform (67-66-3)) |
|---|---|
| Boiling point | 429.4±40.0 °C(Predicted) |
| Density | 1.163±0.06 g/cm3(Predicted) |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 9.88±0.26(Predicted) |
| LogP | 3.710 (est) |
4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol Chemical Properties,Uses,Production
Description
Hinokiresinol (trans-hinokiresinol) and nyasol (cis-hinokiresinol) possess appreciable estrogen receptor binding activity, they can stimulate the proliferation of estrogen- dependent T47D breast cancer cells, and their stimulatory effects could be blocked by an estrogen antagonist, indicating that they are estrogen agonists. trans- and cis-Hinokiresinols have similar free radical scavenging and anti-inflammatory activities, they also have anti-ischemic effects, only trans-hinokiresinol can significantly decrease neuronal injury in cultured cortical neurons exposed to oxygen-glucose deprivation followed by re-oxygenation. 3. Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils. 4. Hinokiresinol has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphylaxis reaction.
Definition
ChEBI: (-)-hinokiresinol is a 1,3-bis(p-hydroxyphenyl)pentane-1,4-diene that has 1E,3S configuration. A natural product found in Chamaecyparis obtusa. It has a role as a metabolite. It is a norlignan and a 1,3-bis(p-hydroxyphenyl)pentane-1,4-diene.
target
Estrogen receptor | NOS | IL Receptor | TNF-α | Progestogen receptor
4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol Preparation Products And Raw materials
Raw materials
Preparation Products
4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 6010 | 61 |
| BioBioPha Co., Ltd. | 0871-65217109 13211707573; | y.liu@mail.biobiopha.com | China | 5654 | 65 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15185 | 58 |
| Shanghai Yongye Biotechnology Co., Ltd. | 86-021-61559134 15921386130 | 3423497944@qq.com | China | 8147 | 55 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 7059 | 55 |