3-Bromoquinoline
- CAS No.
- 5332-24-1
- Chemical Name:
- 3-Bromoquinoline
- Synonyms
- Quinoline, 3-bromo-;NSC 3995;CETH-016;3-BromoquinoL;Bromoquinoline;3-BROMOQUINOLINE;3-BROMOQUINLIINE;3-bromo-quinolin;3-Bromoquinoline >Quinolin-3-yl broMide
- CBNumber:
- CB4220082
- Molecular Formula:
- C9H6BrN
- Molecular Weight:
- 208.05
- MDL Number:
- MFCD00006767
- MOL File:
- 5332-24-1.mol
- MSDS File:
- SDS
| Melting point | 13-15 °C (lit.) |
|---|---|
| Boiling point | 274-276 °C (lit.) |
| Density | 1.533 g/mL at 25 °C (lit.) |
| vapor pressure | 0.196Pa at 25℃ |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | Liquid |
| pka | 2.69(at 25℃) |
| color | Clear colorless to yellow |
| Water Solubility | 103mg/L at 25℃ |
| BRN | 112939 |
| InChIKey | ZGIKWINFUGEQEO-UHFFFAOYSA-N |
| LogP | 3.03 |
| CAS DataBase Reference | 5332-24-1(CAS DataBase Reference) |
| FDA UNII | ZRP57JF73Z |
| NIST Chemistry Reference | Quinoline, 3-bromo-(5332-24-1) |
| EPA Substance Registry System | Quinoline, 3-bromo- (5332-24-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| RIDADR | UN2810 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29334900 | |||||||||
| NFPA 704 |
|
3-Bromoquinoline price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 124133 | 3-Bromoquinoline 98% | 5332-24-1 | 25g | $119 | 2024-03-01 | Buy |
| Sigma-Aldrich | 124133 | 3-Bromoquinoline 98% | 5332-24-1 | 100g | $319 | 2024-03-01 | Buy |
| TCI Chemical | B1013 | 3-Bromoquinoline >98.0%(GC)(T) | 5332-24-1 | 25g | $94 | 2024-03-01 | Buy |
| Alfa Aesar | A14573 | 3-Bromoquinoline, 98% | 5332-24-1 | 10g | $30.65 | 2024-03-01 | Buy |
| Alfa Aesar | A14573 | 3-Bromoquinoline, 98% | 5332-24-1 | 50g | $113.65 | 2024-03-01 | Buy |
3-Bromoquinoline Chemical Properties,Uses,Production
Bromoquinoline
There are seven position isomers with the main properties are as follows:
(2399.79Pa)
Application and synthesis method
3-Bromoquinoline can have action with mixed acid to generate 3-bromo-5-nitroquinoline, followed by heating with potassium permanganate to be oxidized to 5-bromo-2, 3-pyridine dicarboxylic acid.
6-bromo-quinoline can be heated together nitric acid to generate 6-bromo-8-nitro-quinoline, followed by reaction with potassium permanganate to be oxidized into 2, 3-pyridinedicarboxylic acid.
2-bromo-quinoline can be manufactured through the reaction between 2-hydroxyquinoline and phosphorus pentabromide
3-bromo-quinoline can be obtained through heating the quinoline perbromide at 180 ° C.
4-bromoquinoline can be obtained through either the heating reaction between 4-hydroxyquinoline and phosphorus pentabromide or by the diazotization reaction of 4-aminoquinoline.
5-bromo-quinoline can be obtained from the heating reaction between m-bromo aniline, glycerol, m-bromonitrobenzene and concentrated sulfuric acid, or through the diazotization reaction of 5-amino-quinoline.
6-bromo-quinoline can be obtained through the heating reaction between p-bromoaniline, glycerol, concentrated sulfuric acid and p-bromo-nitrobenzene.
7-bromoquinoline can be obtained through the diazotization of 7-aminoquinoline.
8-bromo-quinoline can be obtained through the heating of o-bromo aniline, glycerol, concentrated sulfuric acid and o-bromo-nitrobenzene in the heating system.
Purposes: as organic synthesis reagents.
Uses
For pharmaceuticals
Medicine, pesticide intermediates
Chemical Properties
colorless to light yellow liquid
Synthesis Reference(s)
The Journal of Organic Chemistry, 27, p. 1318, 1962 DOI: 10.1021/jo01051a047
General Description
3-Bromoquinoline undergoes bromine-magnesium exchange reaction with lithium tributylmagnesate in toluene at -10°C, which is quenched by various electrophiles to yield functionalized quinolines.
Flammability and Explosibility
Not classified
3-Bromoquinoline Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 6709 | 58 |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Henan Xiangtong Chemical Co., Ltd. | 86-371-61312303 | info@hnxtchem.com | CHINA | 292 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
View Lastest Price from 3-Bromoquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-02-23 | 3-Bromoquinoline
5332-24-1
|
US $11.00-119.00 / g | 25g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
 |
2022-10-13 | 3-Bromoquinoline
5332-24-1
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2022-03-04 | 3-Bromoquinoline
5332-24-1
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited |
-
- 3-Bromoquinoline
5332-24-1
- US $11.00-119.00 / g
- 0.98
- Shanghai UCHEM Inc.
-
- 3-Bromoquinoline
5332-24-1
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 3-Bromoquinoline
5332-24-1
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited