Ketone Ester
- CAS No.
- 1208313-97-6
- Chemical Name:
- Ketone Ester
- Synonyms
- (R)-3-hydroxybutyl (R)-3-hydroxybutyrate;[(3R)-3-hydroxybutyl] (3R)-3-hydroxybutanoate;R-BHB;BD-AcAc 2;Ketone Ester;Ketone Ester (R-BHB);(R)-(R)-3-hydroxybutyl 3-hydroxybutanoate;(3R)-3-Hydroxybutanoic acid (3R)-3-hydroxybutyl ester;Butanoic acid, 3-hydroxy-, (3R)-3-hydroxybutyl ester, (3R)-;Ketone,endurance,blood glucose,nutritional ketones,BDAcAc 2,diabetes,muscle weakness,Inhibitor,exercise performance,Parkinson’s disease,BD AcAc 2,inhibit,(R,R)-Ketone Ester
- CBNumber:
- CB42628004
- Molecular Formula:
- C8H16O4
- Molecular Weight:
- 176.21
- MDL Number:
- MFCD22417094
- MOL File:
- 1208313-97-6.mol
| Boiling point | 269℃ |
|---|---|
| Density | 1.102 |
| Flash point | 101℃ |
| storage temp. | Store at -20°C |
| solubility | Methyl Acetate: 50 mg/ml |
| pka | 14.38±0.20(Predicted) |
| InChI | InChI=1S/C8H16O4/c1-6(9)3-4-12-8(11)5-7(2)10/h6-7,9-10H,3-5H2,1-2H3/t6-,7-/m1/s1 |
| InChIKey | AOWPVIWVMWUSBD-RNFRBKRXSA-N |
| SMILES | C(OCC[C@H](O)C)(=O)C[C@H](O)C |
| FDA UNII | X587FW0372 |
Ketone Ester Chemical Properties,Uses,Production
Uses
Ketone ester is exogenous ketone bodies that may promote ketosis in humans. Studies on animals have shown that ketone esters can have positive effects on Alzheimer's disease by decreasing amyloid buildup, reducing neurofibrillary tangles and tau, and enhancing learning and memory.
Preparation
Ketone ester can be prepared by reacting (3R)-3-hydroxybutyl methyl ester with tert-butyl dimethylchlorosilane.
benefits
Ketone esters can help with muscle recovery after exercising. They increase the rate of energy store replenishment in the body and support the process of rebuilding muscles. They also decrease the amount of muscle breakdown. The various forms of ketone esters that have been utilized include R,S-1,3-butanediol diacetoacetate (BD-AcAc2, ketone diester), D-β-hydroxybutyrate-(R)-1,3 butanediol (ketone monoester), and Bis-hexanoyl (R)-1,3-butanediol (BH-BD), among others.?
Biological Activity
Ketone ester–enriched diets that induce sustained ketonemia reduce pathological cardiac remodeling and enhance ventricular function in multiple heart failure models across both mice and rats using both prevention and treatment strategies.
Safety
Taking ketone supplements can cause extreme stomach upset in some people. This side effect can limit the number of supplements that a person can take. Taking ketone salts also increases the risk of electrolyte imbalances. Electrolytes are vital for the conduction of electrical signals in the muscles and neurons.
in vivo
Blood glucose decreased by about 50% from 5 to 2.8 mM while insulin decreased from 0.54 to 0.26 ng/ml in rats fed a diet where 30% of the calories from starch were replaced with ketone esters (20). Plasma leptin was also decreased from 3.12 to 1.83 ng/ml in rats, where ketone esters were substituted equi-calorically for starch. The ability of the metabolism of ketone bodies to increase insulin sensitivity has been demonstrated previously in the working perfused rat heart[1].
References
[1] Veech R, High electron mobility triazine for lower driving voltage and higher efficiency organic light emitting devices. Journal of Lipid Research, 2014; 55: 2004-2006.
Ketone Ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Maintain Biotech Co., Ltd. | +86-75589664337 +86-15112661142 | cami@maintain-bio.com | China | 66 | 58 |
| ZhenYiBio Technology Inc | +8615309206328 | alexxue@zhenyibio.com | China | 299 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales05@airuikechemical.com | China | 994 | 58 |
| Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 | bj1@bj-chem.com | China | 298 | 55 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12471 | 58 |
| Wuhan Haorong Biotechnology Co.,ltd | +8618565342920 | sales@chembj.net | China | 270 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 3001 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7019 | 58 |
Related articles
- Ketone Ester: Bioconversion, Effects on Metabolism and Transcription
- Ketone ester decrease glucose and insulin, influence transcription, and aid ketone delivery, offering metabolic health benefit....
- Apr 10，2024
- Generation and Uses of Ketone Bodies
- Ketone Ester is an orally available ketone monoester that acts as a precursor to ketone bodies. Ketone bodies exert ester-gene....
- Nov 14，2023
- The introduction of Ketone Ester
- The Ketone Ester, with the CAS No: 1208313-97-6, is also known as (3R)-3-Hydroxybutanoic acid (3R)-3-hydroxybutyl ester. This ....
- Jan 11，2023
View Lastest Price from Ketone Ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-21 | Ketone Ester
1208313-97-6
|
US $0.00-0.00 / kg | 1kg | 99% | 500 | Wuhan Haorong Biotechnology Co.,Ltd | |
 |
2024-04-27 | Ketone Ester
1208313-97-6
|
US $50.00 / kg | 1kg | 99.10% | 50000kg | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2024-04-18 | Ketone Ester / R-BHB
1208313-97-6
|
US $0.00-0.00 / KG | 1KG | 99 | 5000 | Hebei Kingfiner Technology Development Co.Ltd |
-
- Ketone Ester
1208313-97-6
- US $0.00-0.00 / kg
- 99%
- Wuhan Haorong Biotechnology Co.,Ltd
-
- Ketone Ester
1208313-97-6
- US $50.00 / kg
- 99.10%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- Ketone Ester / R-BHB
1208313-97-6
- US $0.00-0.00 / KG
- 99
- Hebei Kingfiner Technology Development Co.Ltd